The interaction of lipids and inflammatory markers predict negative symptom severity in patients with schizophrenia

David R. Goldsmith, Nicholas Massa, Brian J. Miller, Andrew H. Miller, Erica Duncan

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Finding biological predictors and novel mechanisms underlying negative symptoms of schizophrenia is of significant importance given the lack of effective treatments. Increasing data support a role for metabolic dysfunction and inflammation in reward processing deficits in psychiatric illness. Herein, we found an interaction between lipids and inflammation as a predictor of worse negative symptom severity in individuals with schizophrenia. Future studies may seek to further elucidate this relationship and thereby reveal novel treatment targets for negative symptoms.

Original languageEnglish (US)
Article number50
Journalnpj Schizophrenia
Volume7
Issue number1
DOIs
StatePublished - Dec 2021

ASJC Scopus subject areas

  • Psychiatry and Mental health

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