@inbook{326bb8fb0f6444e68b3f4adcd480f2ac,
title = "The mitochondrial Na+/Ca2+ exchanger is necessary but not sufficient for Ca2+ homeostasis and viability",
abstract = "Luongo et al. found that the mitochondrial Na+/Ca2+ exchanger (NCLX) was essential for Ca2+ homeostasis and viability. Here, we re-analyze their data in terms of fractal self-similarity and quantitative difference (QD). We calculated the 7-dimension data from NCLX conditional loss-of-function mouse models, and the 9-dimension data from NCLX overexpression (NCLX-Tg) models. Results: The 9-dimension data of the NCLX-Tg and its tTA control were partially self-similar to each other, while the 7-dimension data in NCLX knockout models were not.Conclusion: The NCLX may be necessary but is not sufficient for Ca2+ homeostasis and viability.",
author = "Liu, {Timon Cheng Yi} and Tang, {Xiao Ming} and Rui Duan and Lei Ma and Ling Zhu and Quanguang Zhang",
note = "Funding Information: Acknowledgments This work was supported by National Science Foundation of China (61575065, 11604104, 31771256), Doctoral Fund of Ministry of Education of China (20124407110013), and Guangdong Scientific Project (2012B031600004). Publisher Copyright: {\textcopyright} 2018, Springer International Publishing AG, part of Springer Nature.",
year = "2018",
doi = "10.1007/978-3-319-91287-5_45",
language = "English (US)",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer New York LLC",
pages = "281--285",
booktitle = "Advances in Experimental Medicine and Biology",
}