Abstract
The histological classification of brain tumors currently is based on the morphological appearance and protein expression patterns that reflect specific cell types within the central nervous system. Recent studies have suggested that the cells of origin for brain tumors may persist in the fully formed tumors, and that these "cancer stem cells" might represent the relevant cellular targets for anticancer therapy. In this regard, insights into the developmental neurobiology of brain tumors has significant impact on our understanding of the molecular and cellular pathogenesis of these devastating cancers, as well as the development of new strategies for treating brain tumors.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3-11 |
| Number of pages | 9 |
| Journal | Annals of Neurology |
| Volume | 60 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 2006 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
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