The predictive value of incidental PET/CT findings suspicious for breast cancer in women with non-breast malignancies

John S. Beatty; Hadyn T Williams; Angela L. Gucwa; Matthew P. Hughes; Viren S. Vasudeva; Beau A. Aldridge; Deborah M. Fields; George David; D. Scott Lind; Edward James Kruse; James M. McLoughlin

doi:10.1016/j.amjsurg.2009.06.009

The predictive value of incidental PET/CT findings suspicious for breast cancer in women with non-breast malignancies

John S. Beatty, Hadyn T Williams, Angela L. Gucwa, Matthew P. Hughes, Viren S. Vasudeva, Beau A. Aldridge, Deborah M. Fields, George David, D. Scott Lind, Edward James Kruse, James M. McLoughlin

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Background: On occasion, patients followed with positron emission tomographic (PET)/computed tomographic (CT) imaging for nonbreast malignancies will have incidental breast findings concerning for second primary breast cancers. The aim of this study was to determine the predictive value of PET/CT imaging to identify breast cancers in these patients. Methods: Patients with primary nonbreast malignancies and findings concerning for second primary breast cancers were identified from a prospectively acquired nuclear medicine database from January 2005 to July 2008. Chart reviews were then performed. Results: Nine hundred two women underwent PET/CT imaging to evaluate nonbreast malignancies. Nine women (1%) had concerning breast findings, and 5 (56%) had subsequent breast cancer diagnoses. The positive predictive value of PET/CT imaging in these patients was 63%. Evidence of compliance with current screening guidelines was present in only 22% of these patients. Conclusions: The data suggest that findings concerning for an additional primary breast cancer should be evaluated and that age-appropriate screening tools should not be abandoned.

Original language	English (US)
Pages (from-to)	495-499
Number of pages	5
Journal	American Journal of Surgery
Volume	198
Issue number	4
DOIs	https://doi.org/10.1016/j.amjsurg.2009.06.009
State	Published - Oct 2009

Keywords

Breast cancer
PET/CT
Second primary malignancy

ASJC Scopus subject areas

Surgery

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.amjsurg.2009.06.009

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Beatty, J. S., Williams, H. T., Gucwa, A. L., Hughes, M. P., Vasudeva, V. S., Aldridge, B. A., Fields, D. M., David, G., Lind, D. S., Kruse, E. J., & McLoughlin, J. M. (2009). The predictive value of incidental PET/CT findings suspicious for breast cancer in women with non-breast malignancies. American Journal of Surgery, 198(4), 495-499. https://doi.org/10.1016/j.amjsurg.2009.06.009

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abstract = "Background: On occasion, patients followed with positron emission tomographic (PET)/computed tomographic (CT) imaging for nonbreast malignancies will have incidental breast findings concerning for second primary breast cancers. The aim of this study was to determine the predictive value of PET/CT imaging to identify breast cancers in these patients. Methods: Patients with primary nonbreast malignancies and findings concerning for second primary breast cancers were identified from a prospectively acquired nuclear medicine database from January 2005 to July 2008. Chart reviews were then performed. Results: Nine hundred two women underwent PET/CT imaging to evaluate nonbreast malignancies. Nine women (1%) had concerning breast findings, and 5 (56%) had subsequent breast cancer diagnoses. The positive predictive value of PET/CT imaging in these patients was 63%. Evidence of compliance with current screening guidelines was present in only 22% of these patients. Conclusions: The data suggest that findings concerning for an additional primary breast cancer should be evaluated and that age-appropriate screening tools should not be abandoned.",

keywords = "Breast cancer, PET/CT, Second primary malignancy",

author = "Beatty, {John S.} and Williams, {Hadyn T} and Gucwa, {Angela L.} and Hughes, {Matthew P.} and Vasudeva, {Viren S.} and Aldridge, {Beau A.} and Fields, {Deborah M.} and George David and Lind, {D. Scott} and Kruse, {Edward James} and McLoughlin, {James M.}",

year = "2009",

month = oct,

doi = "10.1016/j.amjsurg.2009.06.009",

language = "English (US)",

volume = "198",

pages = "495--499",

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AU - Beatty, John S.

AU - Williams, Hadyn T

AU - Gucwa, Angela L.

AU - Hughes, Matthew P.

AU - Vasudeva, Viren S.

AU - Aldridge, Beau A.

AU - Fields, Deborah M.

AU - David, George

AU - Lind, D. Scott

AU - Kruse, Edward James

AU - McLoughlin, James M.

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N2 - Background: On occasion, patients followed with positron emission tomographic (PET)/computed tomographic (CT) imaging for nonbreast malignancies will have incidental breast findings concerning for second primary breast cancers. The aim of this study was to determine the predictive value of PET/CT imaging to identify breast cancers in these patients. Methods: Patients with primary nonbreast malignancies and findings concerning for second primary breast cancers were identified from a prospectively acquired nuclear medicine database from January 2005 to July 2008. Chart reviews were then performed. Results: Nine hundred two women underwent PET/CT imaging to evaluate nonbreast malignancies. Nine women (1%) had concerning breast findings, and 5 (56%) had subsequent breast cancer diagnoses. The positive predictive value of PET/CT imaging in these patients was 63%. Evidence of compliance with current screening guidelines was present in only 22% of these patients. Conclusions: The data suggest that findings concerning for an additional primary breast cancer should be evaluated and that age-appropriate screening tools should not be abandoned.

AB - Background: On occasion, patients followed with positron emission tomographic (PET)/computed tomographic (CT) imaging for nonbreast malignancies will have incidental breast findings concerning for second primary breast cancers. The aim of this study was to determine the predictive value of PET/CT imaging to identify breast cancers in these patients. Methods: Patients with primary nonbreast malignancies and findings concerning for second primary breast cancers were identified from a prospectively acquired nuclear medicine database from January 2005 to July 2008. Chart reviews were then performed. Results: Nine hundred two women underwent PET/CT imaging to evaluate nonbreast malignancies. Nine women (1%) had concerning breast findings, and 5 (56%) had subsequent breast cancer diagnoses. The positive predictive value of PET/CT imaging in these patients was 63%. Evidence of compliance with current screening guidelines was present in only 22% of these patients. Conclusions: The data suggest that findings concerning for an additional primary breast cancer should be evaluated and that age-appropriate screening tools should not be abandoned.

KW - Breast cancer

KW - PET/CT

KW - Second primary malignancy

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The predictive value of incidental PET/CT findings suspicious for breast cancer in women with non-breast malignancies

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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