The role of gadolinium-DTPA-enhanced magnetic resonance imaging in presurgical evaluation for intractable partial epilepsy

James W. Wheless; R. E. Figueroa-Ortiz; E. F. Binet; D. W. King; B. B. Gallagher; A. M. Murro; H. F. Flanigin; J. R. Smith; M. M. Leveridge

doi:10.1016/S0896-6974(05)80067-2

The role of gadolinium-DTPA-enhanced magnetic resonance imaging in presurgical evaluation for intractable partial epilepsy

James W. Wheless, R. E. Figueroa-Ortiz, E. F. Binet, D. W. King, B. B. Gallagher, A. M. Murro, H. F. Flanigin, J. R. Smith, M. M. Leveridge

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Abstract

In order to evaluate the diagnostic efficacy of gadolinium-DTPA (Gd-DTPA), we performed enhanced and unenhanced magnetic resonance imaging (MRI) of the head in 48 Phase I presurgical patients. Fifty-two percent had normal MRI (unenhanced and enhanced). Forty-eight percent had abnormal unenhanced MRI. Gd-DTPA MRI was helpful preoperatively in 57% of these patients. Gd-DTPA improves the diagnostic sensitivity of MRI and provides important additional information in the presurgical evaluation of patients with partial epilepsy only if the unenhanced MRI is abnormal.

Original language	English (US)
Pages (from-to)	95-101
Number of pages	7
Journal	Journal of Epilepsy
Volume	4
Issue number	2
DOIs	https://doi.org/10.1016/S0896-6974(05)80067-2
State	Published - 1991

Keywords

Epilepsy surgery
Gadolinium-DTPA
Intractable partial seizures
Magnetic resonance imaging

ASJC Scopus subject areas

Neuroscience(all)
Clinical Neurology

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10.1016/S0896-6974(05)80067-2

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title = "The role of gadolinium-DTPA-enhanced magnetic resonance imaging in presurgical evaluation for intractable partial epilepsy",

abstract = "In order to evaluate the diagnostic efficacy of gadolinium-DTPA (Gd-DTPA), we performed enhanced and unenhanced magnetic resonance imaging (MRI) of the head in 48 Phase I presurgical patients. Fifty-two percent had normal MRI (unenhanced and enhanced). Forty-eight percent had abnormal unenhanced MRI. Gd-DTPA MRI was helpful preoperatively in 57% of these patients. Gd-DTPA improves the diagnostic sensitivity of MRI and provides important additional information in the presurgical evaluation of patients with partial epilepsy only if the unenhanced MRI is abnormal.",

keywords = "Epilepsy surgery, Gadolinium-DTPA, Intractable partial seizures, Magnetic resonance imaging",

author = "Wheless, {James W.} and Figueroa-Ortiz, {R. E.} and Binet, {E. F.} and King, {D. W.} and Gallagher, {B. B.} and Murro, {A. M.} and Flanigin, {H. F.} and Smith, {J. R.} and Leveridge, {M. M.}",

year = "1991",

doi = "10.1016/S0896-6974(05)80067-2",

language = "English (US)",

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AU - Wheless, James W.

AU - Figueroa-Ortiz, R. E.

AU - Binet, E. F.

AU - King, D. W.

AU - Gallagher, B. B.

AU - Murro, A. M.

AU - Flanigin, H. F.

AU - Smith, J. R.

AU - Leveridge, M. M.

PY - 1991

Y1 - 1991

N2 - In order to evaluate the diagnostic efficacy of gadolinium-DTPA (Gd-DTPA), we performed enhanced and unenhanced magnetic resonance imaging (MRI) of the head in 48 Phase I presurgical patients. Fifty-two percent had normal MRI (unenhanced and enhanced). Forty-eight percent had abnormal unenhanced MRI. Gd-DTPA MRI was helpful preoperatively in 57% of these patients. Gd-DTPA improves the diagnostic sensitivity of MRI and provides important additional information in the presurgical evaluation of patients with partial epilepsy only if the unenhanced MRI is abnormal.

AB - In order to evaluate the diagnostic efficacy of gadolinium-DTPA (Gd-DTPA), we performed enhanced and unenhanced magnetic resonance imaging (MRI) of the head in 48 Phase I presurgical patients. Fifty-two percent had normal MRI (unenhanced and enhanced). Forty-eight percent had abnormal unenhanced MRI. Gd-DTPA MRI was helpful preoperatively in 57% of these patients. Gd-DTPA improves the diagnostic sensitivity of MRI and provides important additional information in the presurgical evaluation of patients with partial epilepsy only if the unenhanced MRI is abnormal.

KW - Epilepsy surgery

KW - Gadolinium-DTPA

KW - Intractable partial seizures

KW - Magnetic resonance imaging

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The role of gadolinium-DTPA-enhanced magnetic resonance imaging in presurgical evaluation for intractable partial epilepsy

Abstract

Keywords

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