TY - JOUR
T1 - The Second International Symposium on the Developmental Aspects of Androgen Excess, Toronto, Canada, 20 June 2000
AU - Azziz, Ricardo
AU - Saenger, Paul
PY - 2000
Y1 - 2000
N2 - Clinical hyperandrogenism, in particular polycystic ovary syndrome (PCOS), affects 4-7% of women of reproductive age, making it one of the most common human reproductive endocrinological abnormalities. However, our understanding of the developmental aspects of these disorders remains limited. The Second International Symposium on the Developmental Aspects of Androgen Excess (Toronto, Canada, 20 June 2000) was held with the purpose of fostering greater investigative communication, consensus and focus. It was felt that a better understanding of PCOS phenotypes was needed; that an aggressive attempt should be made to continue to expand the molecular genetic studies of the disorder; that research into the role and mechanism(s) underlying the associated defects in insulin action and signaling should be continued; that longitudinal studies, particularly those focusing on the role of intrauterine stress and malnutrition, and premature adrenarche, on the development of PCOS were warranted; and that an improved understanding of the molecular defects in steroidogenesis present in PCOS is needed.
AB - Clinical hyperandrogenism, in particular polycystic ovary syndrome (PCOS), affects 4-7% of women of reproductive age, making it one of the most common human reproductive endocrinological abnormalities. However, our understanding of the developmental aspects of these disorders remains limited. The Second International Symposium on the Developmental Aspects of Androgen Excess (Toronto, Canada, 20 June 2000) was held with the purpose of fostering greater investigative communication, consensus and focus. It was felt that a better understanding of PCOS phenotypes was needed; that an aggressive attempt should be made to continue to expand the molecular genetic studies of the disorder; that research into the role and mechanism(s) underlying the associated defects in insulin action and signaling should be continued; that longitudinal studies, particularly those focusing on the role of intrauterine stress and malnutrition, and premature adrenarche, on the development of PCOS were warranted; and that an improved understanding of the molecular defects in steroidogenesis present in PCOS is needed.
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U2 - 10.1016/S1043-2760(00)00319-2
DO - 10.1016/S1043-2760(00)00319-2
M3 - Article
C2 - 11273567
AN - SCOPUS:0033793282
SN - 1043-2760
VL - 11
SP - 338
EP - 340
JO - Trends in Endocrinology and Metabolism
JF - Trends in Endocrinology and Metabolism
IS - 8
ER -