The use of high-dose hydroxocobalamin for vasoplegic syndrome

Joseph D. Roderique, Kofi Vandyck, Brita Holman, Daniel Tang, Betty Chui, Bruce D. Spiess

Research output: Contribution to journalArticlepeer-review

64 Scopus citations


We describe a case of hypotension on cardiopulmonary bypass for coronary artery bypass grafting, double valve repairs, and patent foramen ovale closure. The patient experienced vasoplegic syndrome while on cardiopulmonary bypass. He was treated with high-dose hydroxocobalamin (vitamin B12). His blood pressure responded rapidly, obviating any further vasopressor requirements.

Original languageEnglish (US)
Pages (from-to)1785-1786
Number of pages2
JournalAnnals of Thoracic Surgery
Issue number5
StatePublished - May 2014
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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