Topography of skeletal muscle ryanodine receptors studied by atomic force microscopy

Q. Q. Wei; S. F. Chen; X. Y. Cheng; X. B. Yu; J. Hu; M. Q. Li; P. H. Zhu

doi:10.1116/1.591252

Topography of skeletal muscle ryanodine receptors studied by atomic force microscopy

Q. Q. Wei, S. F. Chen, X. Y. Cheng, X. B. Yu, J. Hu, M. Q. Li, P. H. Zhu

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Tapping mode atomic force microscopy is demonstrated for topographic investigation of isolated ryanodine receptors of rabbit skeletal muscle (RyR1) both in air and in a buffer. In air, the micrographs appeared to have four-fold symmetry and showed two different configurations depending on the presence or absence of a center protrusion. Despite the squareness of the images discerned of RyR1s in the buffer, the detailed topography of RyR1 appeared different from that in air. Possible reasons for this are discussed.

Original language	English (US)
Pages (from-to)	636-638
Number of pages	3
Journal	Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures
Volume	18
Issue number	2
DOIs	https://doi.org/10.1116/1.591252
State	Published - Mar 2000
Externally published	Yes

ASJC Scopus subject areas

Condensed Matter Physics
Electrical and Electronic Engineering

Access to Document

10.1116/1.591252

Cite this

@article{ad1b76d8833741a4b123de5407893c7c,

title = "Topography of skeletal muscle ryanodine receptors studied by atomic force microscopy",

abstract = "Tapping mode atomic force microscopy is demonstrated for topographic investigation of isolated ryanodine receptors of rabbit skeletal muscle (RyR1) both in air and in a buffer. In air, the micrographs appeared to have four-fold symmetry and showed two different configurations depending on the presence or absence of a center protrusion. Despite the squareness of the images discerned of RyR1s in the buffer, the detailed topography of RyR1 appeared different from that in air. Possible reasons for this are discussed.",

author = "Wei, {Q. Q.} and Chen, {S. F.} and Cheng, {X. Y.} and Yu, {X. B.} and J. Hu and Li, {M. Q.} and Zhu, {P. H.}",

year = "2000",

month = mar,

doi = "10.1116/1.591252",

language = "English (US)",

volume = "18",

pages = "636--638",

journal = "Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures",

issn = "1071-1023",

publisher = "AVS Science and Technology Society",

number = "2",

}

TY - JOUR

T1 - Topography of skeletal muscle ryanodine receptors studied by atomic force microscopy

AU - Wei, Q. Q.

AU - Chen, S. F.

AU - Cheng, X. Y.

AU - Yu, X. B.

AU - Hu, J.

AU - Li, M. Q.

AU - Zhu, P. H.

PY - 2000/3

Y1 - 2000/3

N2 - Tapping mode atomic force microscopy is demonstrated for topographic investigation of isolated ryanodine receptors of rabbit skeletal muscle (RyR1) both in air and in a buffer. In air, the micrographs appeared to have four-fold symmetry and showed two different configurations depending on the presence or absence of a center protrusion. Despite the squareness of the images discerned of RyR1s in the buffer, the detailed topography of RyR1 appeared different from that in air. Possible reasons for this are discussed.

AB - Tapping mode atomic force microscopy is demonstrated for topographic investigation of isolated ryanodine receptors of rabbit skeletal muscle (RyR1) both in air and in a buffer. In air, the micrographs appeared to have four-fold symmetry and showed two different configurations depending on the presence or absence of a center protrusion. Despite the squareness of the images discerned of RyR1s in the buffer, the detailed topography of RyR1 appeared different from that in air. Possible reasons for this are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0034156293&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034156293&partnerID=8YFLogxK

U2 - 10.1116/1.591252

DO - 10.1116/1.591252

M3 - Article

AN - SCOPUS:0034156293

SN - 1071-1023

VL - 18

SP - 636

EP - 638

JO - Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures

JF - Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures

IS - 2

ER -

Topography of skeletal muscle ryanodine receptors studied by atomic force microscopy

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this