TY - JOUR
T1 - Trigeminal trophic syndrome from stroke
T2 - An under-recognized central neuropathic itch syndrome
AU - Curtis, Ashley R.
AU - Oaklander, Anne L.
AU - Johnson, Annette
AU - Yosipovitch, Gil
PY - 2012
Y1 - 2012
N2 - Trigeminal trophic syndrome (TTS) is the historic name for neuropathic self-induced facial ulceration from abnormal sensory symptoms leading to uncontrolled scratching. Anatomic co-localization of sensory loss (numbness) plus neuropathic itch and pain permits painless scratching. If the itch is severe, some patients will scratch to the point of causing self-injury. Patients may be unaware or may conceal the fact that their lesions are self-induced and thus the diagnosis presents a clinical challenge. Many cases remain undiagnosed, leading to unnecessary and ineffective tests, procedures, and prescribing. We document a patient with a central cause of TTS multiple cerebral vascular accidents and summarize the presentation, pathogenesis, and treatment options.
AB - Trigeminal trophic syndrome (TTS) is the historic name for neuropathic self-induced facial ulceration from abnormal sensory symptoms leading to uncontrolled scratching. Anatomic co-localization of sensory loss (numbness) plus neuropathic itch and pain permits painless scratching. If the itch is severe, some patients will scratch to the point of causing self-injury. Patients may be unaware or may conceal the fact that their lesions are self-induced and thus the diagnosis presents a clinical challenge. Many cases remain undiagnosed, leading to unnecessary and ineffective tests, procedures, and prescribing. We document a patient with a central cause of TTS multiple cerebral vascular accidents and summarize the presentation, pathogenesis, and treatment options.
KW - Cerebral-infarction
KW - Imaging
KW - Neuropathic-pain
KW - Pruritus
KW - Self-injurious-behavior.
KW - Stroke
KW - Trigeminal-neuralgia
UR - http://www.scopus.com/inward/record.url?scp=84856589334&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84856589334&partnerID=8YFLogxK
U2 - 10.2165/11594060-000000000-00000
DO - 10.2165/11594060-000000000-00000
M3 - Article
C2 - 22220970
AN - SCOPUS:84856589334
SN - 1175-0561
VL - 13
SP - 125
EP - 128
JO - American Journal of Clinical Dermatology
JF - American Journal of Clinical Dermatology
IS - 2
ER -