Unphosphorylated STAT1 promotes sarcoma development through repressing expression of fas and bad and conferring apoptotic resistance

Keyphrases

• Soft Tissue Sarcoma 100%
• Sarcoma 100%
• Apoptotic Resistance 100%
• ISTAT 85%
• Sarcoma Cells 42%
• Interferon Regulatory Factor 8 (IRF8) 42%
• Tumor Cells 28%
• Human Soft Tissue 28%
• Fas-mediated Apoptosis 28%
• Disease-specific Survival 28%
• Tumor Suppressor 14%
• Human Cancer 14%
• Gene Promoter 14%
• Murine Model 14%
• Phosphorylation State 14%
• Tumor Promoter 14%
• Metastatic Potential 14%
• Hypermethylated 14%
• Immune Escape 14%
• RNA Interference 14%
• Effector Molecules 14%
• Cancer Immunosurveillance 14%
• IFN Signaling Pathway 14%
• Ill-defined 14%
• Mechanistic Investigation 14%

Immunology and Microbiology

• Soft Tissue 100%
• STAT1 100%
• Promoter Region 42%
• Sarcoma Cell 42%
• IRF8 42%
• Tumor Cell 28%
• Mediator 28%
• Disease Specific Survival 28%
• Signal Transduction 14%
• RNA Interference 14%
• Immune Escape 14%
• Immunosurveillance 14%

Biochemistry, Genetics and Molecular Biology

• STAT1 100%
• IRF8 42%
• Promoter Region 28%
• Mediator 28%
• Disease Specific Survival 28%
• Tumor Suppressor Protein 14%
• Transcription 14%
• Signal Transduction 14%
• Gene Promoter 14%
• RNA Interference 14%
• Immunosurveillance 14%