Use of 3.0-T MRI for stereotactic radiosurgery planning for treatment of brain metastases: A single-institution retrospective review

Paul A. Saconn; Edward G. Shaw; Michael D. Chan; Sarah E. Squire; Annette Johnson; Kevin P. McMullen; Stephen B. Tatter; Thomas L. Ellis; James Lovato; J. Daniel Bourland; Kenneth E. Ekstrand; Allan F. Deguzman; Michael T. Munley

doi:10.1016/j.ijrobp.2010.05.049

Use of 3.0-T MRI for stereotactic radiosurgery planning for treatment of brain metastases: A single-institution retrospective review

Paul A. Saconn, Edward G. Shaw, Michael D. Chan, Sarah E. Squire, Annette Johnson, Kevin P. McMullen, Stephen B. Tatter, Thomas L. Ellis, James Lovato, J. Daniel Bourland, Kenneth E. Ekstrand, Allan F. Deguzman, Michael T. Munley

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Purpose: To investigate the efficacy of 3.0-T magnetic resonance imaging (MRI) for detecting brain metastases for stereotactic radiosurgery (SRS) planning. Methods and Materials: All adult patients scheduled for SRS treatment for brain metastases at our institution between October 2005 and January 2008 were eligible for analysis. All patients underwent radiosurgery treatment planning 3.0-T MRI on the day of scheduled radiosurgery and a diagnostic 1.5-T MRI in the days or weeks prior to radiosurgery for comparison. Both scans were interpreted by neuroradiologists who reported their findings in the radiology reports. We performed a retrospective review of the radiology reports to determine the number of brain metastases identified using each MRI system. Results: Of 254 patients scheduled for treatment from October 2005 to January 2008, 138 patients had radiology reports that explicitly described the number of metastases identified on both scans. With a median interval of 17 days (range, 1-82) between scans, the number of metastases detected using 1.5-T MRI system ranged from 1 to 5 and from 1 to 8 using the 3.0 T-MRI system. Twenty-two percent of patients were found to have a greater number of metastases with the 3.0 T-MRI system. The difference in number of metastases detected between the two scans for the entire cohort ranged from 0 to 6. Neither histology (p = 0.52 by chi-sq test) nor time between scans (p = 0.62 by linear regression) were significantly associated with the difference in number of metastases between scans. Conclusions: The 3.0-T MRI system appears to be superior to a 1.5-T MRI system for detecting brain metastases, which may have significant implications in determining the appropriate treatment modality. Our findings suggest the need for a prospectively designed study to further evaluate the use of a 3.0 T-MRI system for stereotactic radiosurgery planning in the treatment of brain metastases.

Original language	English (US)
Pages (from-to)	1142-1146
Number of pages	5
Journal	International Journal of Radiation Oncology Biology Physics
Volume	78
Issue number	4
DOIs	https://doi.org/10.1016/j.ijrobp.2010.05.049
State	Published - Nov 4 2010
Externally published	Yes

Keywords

Brain metastases
MRI
Radiosurgery

ASJC Scopus subject areas

Radiation
Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ijrobp.2010.05.049

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Saconn, P. A., Shaw, E. G., Chan, M. D., Squire, S. E., Johnson, A., McMullen, K. P., Tatter, S. B., Ellis, T. L., Lovato, J., Bourland, J. D., Ekstrand, K. E., Deguzman, A. F., & Munley, M. T. (2010). Use of 3.0-T MRI for stereotactic radiosurgery planning for treatment of brain metastases: A single-institution retrospective review. International Journal of Radiation Oncology Biology Physics, 78(4), 1142-1146. https://doi.org/10.1016/j.ijrobp.2010.05.049

Saconn, PA, Shaw, EG, Chan, MD, Squire, SE, Johnson, A, McMullen, KP, Tatter, SB, Ellis, TL, Lovato, J, Bourland, JD, Ekstrand, KE, Deguzman, AF & Munley, MT 2010, 'Use of 3.0-T MRI for stereotactic radiosurgery planning for treatment of brain metastases: A single-institution retrospective review', International Journal of Radiation Oncology Biology Physics, vol. 78, no. 4, pp. 1142-1146. https://doi.org/10.1016/j.ijrobp.2010.05.049

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title = "Use of 3.0-T MRI for stereotactic radiosurgery planning for treatment of brain metastases: A single-institution retrospective review",

abstract = "Purpose: To investigate the efficacy of 3.0-T magnetic resonance imaging (MRI) for detecting brain metastases for stereotactic radiosurgery (SRS) planning. Methods and Materials: All adult patients scheduled for SRS treatment for brain metastases at our institution between October 2005 and January 2008 were eligible for analysis. All patients underwent radiosurgery treatment planning 3.0-T MRI on the day of scheduled radiosurgery and a diagnostic 1.5-T MRI in the days or weeks prior to radiosurgery for comparison. Both scans were interpreted by neuroradiologists who reported their findings in the radiology reports. We performed a retrospective review of the radiology reports to determine the number of brain metastases identified using each MRI system. Results: Of 254 patients scheduled for treatment from October 2005 to January 2008, 138 patients had radiology reports that explicitly described the number of metastases identified on both scans. With a median interval of 17 days (range, 1-82) between scans, the number of metastases detected using 1.5-T MRI system ranged from 1 to 5 and from 1 to 8 using the 3.0 T-MRI system. Twenty-two percent of patients were found to have a greater number of metastases with the 3.0 T-MRI system. The difference in number of metastases detected between the two scans for the entire cohort ranged from 0 to 6. Neither histology (p = 0.52 by chi-sq test) nor time between scans (p = 0.62 by linear regression) were significantly associated with the difference in number of metastases between scans. Conclusions: The 3.0-T MRI system appears to be superior to a 1.5-T MRI system for detecting brain metastases, which may have significant implications in determining the appropriate treatment modality. Our findings suggest the need for a prospectively designed study to further evaluate the use of a 3.0 T-MRI system for stereotactic radiosurgery planning in the treatment of brain metastases.",

keywords = "Brain metastases, MRI, Radiosurgery",

author = "Saconn, {Paul A.} and Shaw, {Edward G.} and Chan, {Michael D.} and Squire, {Sarah E.} and Annette Johnson and McMullen, {Kevin P.} and Tatter, {Stephen B.} and Ellis, {Thomas L.} and James Lovato and Bourland, {J. Daniel} and Ekstrand, {Kenneth E.} and Deguzman, {Allan F.} and Munley, {Michael T.}",

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T1 - Use of 3.0-T MRI for stereotactic radiosurgery planning for treatment of brain metastases

T2 - A single-institution retrospective review

AU - Saconn, Paul A.

AU - Shaw, Edward G.

AU - Chan, Michael D.

AU - Squire, Sarah E.

AU - Johnson, Annette

AU - McMullen, Kevin P.

AU - Tatter, Stephen B.

AU - Ellis, Thomas L.

AU - Lovato, James

AU - Bourland, J. Daniel

AU - Ekstrand, Kenneth E.

AU - Deguzman, Allan F.

AU - Munley, Michael T.

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Y1 - 2010/11/4

N2 - Purpose: To investigate the efficacy of 3.0-T magnetic resonance imaging (MRI) for detecting brain metastases for stereotactic radiosurgery (SRS) planning. Methods and Materials: All adult patients scheduled for SRS treatment for brain metastases at our institution between October 2005 and January 2008 were eligible for analysis. All patients underwent radiosurgery treatment planning 3.0-T MRI on the day of scheduled radiosurgery and a diagnostic 1.5-T MRI in the days or weeks prior to radiosurgery for comparison. Both scans were interpreted by neuroradiologists who reported their findings in the radiology reports. We performed a retrospective review of the radiology reports to determine the number of brain metastases identified using each MRI system. Results: Of 254 patients scheduled for treatment from October 2005 to January 2008, 138 patients had radiology reports that explicitly described the number of metastases identified on both scans. With a median interval of 17 days (range, 1-82) between scans, the number of metastases detected using 1.5-T MRI system ranged from 1 to 5 and from 1 to 8 using the 3.0 T-MRI system. Twenty-two percent of patients were found to have a greater number of metastases with the 3.0 T-MRI system. The difference in number of metastases detected between the two scans for the entire cohort ranged from 0 to 6. Neither histology (p = 0.52 by chi-sq test) nor time between scans (p = 0.62 by linear regression) were significantly associated with the difference in number of metastases between scans. Conclusions: The 3.0-T MRI system appears to be superior to a 1.5-T MRI system for detecting brain metastases, which may have significant implications in determining the appropriate treatment modality. Our findings suggest the need for a prospectively designed study to further evaluate the use of a 3.0 T-MRI system for stereotactic radiosurgery planning in the treatment of brain metastases.

AB - Purpose: To investigate the efficacy of 3.0-T magnetic resonance imaging (MRI) for detecting brain metastases for stereotactic radiosurgery (SRS) planning. Methods and Materials: All adult patients scheduled for SRS treatment for brain metastases at our institution between October 2005 and January 2008 were eligible for analysis. All patients underwent radiosurgery treatment planning 3.0-T MRI on the day of scheduled radiosurgery and a diagnostic 1.5-T MRI in the days or weeks prior to radiosurgery for comparison. Both scans were interpreted by neuroradiologists who reported their findings in the radiology reports. We performed a retrospective review of the radiology reports to determine the number of brain metastases identified using each MRI system. Results: Of 254 patients scheduled for treatment from October 2005 to January 2008, 138 patients had radiology reports that explicitly described the number of metastases identified on both scans. With a median interval of 17 days (range, 1-82) between scans, the number of metastases detected using 1.5-T MRI system ranged from 1 to 5 and from 1 to 8 using the 3.0 T-MRI system. Twenty-two percent of patients were found to have a greater number of metastases with the 3.0 T-MRI system. The difference in number of metastases detected between the two scans for the entire cohort ranged from 0 to 6. Neither histology (p = 0.52 by chi-sq test) nor time between scans (p = 0.62 by linear regression) were significantly associated with the difference in number of metastases between scans. Conclusions: The 3.0-T MRI system appears to be superior to a 1.5-T MRI system for detecting brain metastases, which may have significant implications in determining the appropriate treatment modality. Our findings suggest the need for a prospectively designed study to further evaluate the use of a 3.0 T-MRI system for stereotactic radiosurgery planning in the treatment of brain metastases.

KW - Brain metastases

KW - MRI

KW - Radiosurgery

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Use of 3.0-T MRI for stereotactic radiosurgery planning for treatment of brain metastases: A single-institution retrospective review

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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