Uterine leiomyosarcoma manifesting as a tricuspid valve mass

Creticus P. Marak, Ana M. Ponea, Narendrakumar Alappan, Shagufta Shaheen, Achuta K. Guddati

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Uterine leiomyosarcoma is a rare malignancy and carries a poorer prognosis when compared to endometrial carcinoma. It has been observed to metastasize to all the major organs. It presents with symptoms of abdominal distension, vaginal bleeding and may pass unnoticed until an advanced stage in patients with leiomyomas. Surgery is a viable option in patients with disease limited to the uterus, but metastasis to the heart may require surgery to prevent acute and catastrophic complications. The case described here involves metastasis to the tricuspid valve, which caused severe tricuspid regurgitation in the setting of acute pulmonary embolism. Surgical resection restored cardiac function and stabilized the patient. This case illustrates a rare site of metastasis of leiomyosarcoma which required immediate intervention and resulted in a favorable outcome.

Original languageEnglish (US)
Pages (from-to)119-126
Number of pages8
JournalCase Reports in Oncology
Issue number1
StatePublished - Jan 2013
Externally publishedYes


  • Leiomyosarcoma
  • Metastasis
  • Pulmonary embolism
  • Tricuspid valve

ASJC Scopus subject areas

  • Oncology


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