Validation of a short cognitive battery to screen for fitness-to-drive of people with multiple sclerosis

A. E. Akinwuntan, D. Backus, J. Grayson, Hannes Devos

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Background and purpose: Some symptoms of multiple sclerosis (MS) affect driving. In a recent study, performance on five cognitive tests predicted the on-road test performance of individuals with relapsing-remitting MS with 91% accuracy, 70% sensitivity and 97% specificity. However, the accuracy with which the battery will predict the driving performance of a different cohort that includes all types of MS is unknown. Methods: Participants (n = 118; 48 ± 9 years of age; 97 females) performed a comprehensive off-road evaluation that lasted about 3 h and a standardized on-road test that lasted approximately 45 min over a 2-day period within the same week. Performance on the five cognitive tests was used to predict participants’ performance on the standardized on-road test. Results: Performance on the five tests together predicted outcome of the on-road test with 82% accuracy, 42% sensitivity and 90% specificity. Conclusions: The accuracy of predicting the on-road performance of a new MS cohort using performance on the battery of five cognitive tests remained very high (82%). The battery, which was administrable in <45 min and cost ~$150, was better at identifying those who actually passed the on-road test (90% specificity). The sensitivity (42%) of the battery indicated that it should not be used as the sole determinant of poor driving-related cognitive skills. A fail performance on the battery should only imply that more comprehensive testing is warranted.

Original languageEnglish (US)
Pages (from-to)1250-1254
Number of pages5
JournalEuropean Journal of Neurology
Issue number10
StatePublished - Oct 2018


  • cognition
  • driving
  • evaluation
  • multiple sclerosis
  • vision

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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