Abstract
Background and purpose: Some symptoms of multiple sclerosis (MS) affect driving. In a recent study, performance on five cognitive tests predicted the on-road test performance of individuals with relapsing-remitting MS with 91% accuracy, 70% sensitivity and 97% specificity. However, the accuracy with which the battery will predict the driving performance of a different cohort that includes all types of MS is unknown. Methods: Participants (n = 118; 48 ± 9 years of age; 97 females) performed a comprehensive off-road evaluation that lasted about 3 h and a standardized on-road test that lasted approximately 45 min over a 2-day period within the same week. Performance on the five cognitive tests was used to predict participants’ performance on the standardized on-road test. Results: Performance on the five tests together predicted outcome of the on-road test with 82% accuracy, 42% sensitivity and 90% specificity. Conclusions: The accuracy of predicting the on-road performance of a new MS cohort using performance on the battery of five cognitive tests remained very high (82%). The battery, which was administrable in <45 min and cost ~$150, was better at identifying those who actually passed the on-road test (90% specificity). The sensitivity (42%) of the battery indicated that it should not be used as the sole determinant of poor driving-related cognitive skills. A fail performance on the battery should only imply that more comprehensive testing is warranted.
Original language | English (US) |
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Pages (from-to) | 1250-1254 |
Number of pages | 5 |
Journal | European Journal of Neurology |
Volume | 25 |
Issue number | 10 |
DOIs | |
State | Published - Oct 2018 |
Keywords
- cognition
- driving
- evaluation
- multiple sclerosis
- vision
ASJC Scopus subject areas
- Neurology
- Clinical Neurology