Validation of a testis specific serine/threonine kinase [TSSK] family and the substrate of TSSK1 & 2, TSKS, as contraceptive targets.

Keyphrases

• Serine-threonine Kinase 100%
• Testis-specific 100%
• Kinase Family 100%
• Contraceptives 100%
• Phosphorylation 66%
• Equatorial Segment 66%
• In Situ Hybridization 33%
• Testicle 33%
• Expression Pattern 33%
• Bioinformatics 33%
• In Vitro Kinase Assay 33%
• Phosphopeptides 33%
• Male Infertility 33%
• High-throughput Screening 33%
• Expression Study 33%
• Human Spermatozoa 33%
• Spermatogonia 33%
• Midpiece 33%
• Centriole 33%
• Spermatocyte 33%
• Mature Spermatozoa 33%
• Drug Design 33%
• Enzyme Binding 33%
• Substrate Interaction 33%
• Asterisk 33%
• Small Molecule Kinase Inhibitors 33%
• Spermicide 33%
• Human Kinome 33%
• Reversible Contraceptives 33%
• Male Contraception 33%
• Inhibitor Screening 33%
• LC-FTMS 33%
• Sperm Tail 33%

Biochemistry, Genetics and Molecular Biology

• Threonine 100%
• Serine 100%
• Kinase 100%
• Phosphotransferase 100%
• Enzyme 25%
• Mouse 25%
• Phosphopeptide 25%
• in Situ Hybridization 25%
• High Throughput Screening 25%
• Tree 25%
• Small Molecule 25%
• Centriole 25%
• AMP-activated Protein Kinase 25%
• Male Fertility 25%
• Spermatogonium 25%
• Kinome 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Phosphotransferase 100%
• Protein Serine Threonine Kinase 100%
• Mouse 50%
• Serine 50%
• Phosphotransferase Inhibitor 50%
• Tree 50%
• Phosphopeptide 50%
• Drug Development 50%
• High-Throughput Screening 50%
• Spermicidal Agent 50%
• Enzyme Interaction 50%