Vein of Galen Malformation Thrombosis by Single-Stage, 2-Coil Embolization

Nathan Todnem, Vamsi Reddy, Miranda Hayworth, Cargill Alleyne

Research output: Contribution to journalArticlepeer-review


Advances in endovascular embolization have improved morbidity and mortality among patients with vein of Galen malformations (VoGMs). The patient presented at 3 months of age with increased head circumference and a bruit over his anterior fontanelle. Diagnostic cerebral angiography confirmed the presence of a large mural-type VoGM. The decision was made to undergo a staged arterial embolization at 4 years of age after developing worsening right-sided hemiparesis. An attempt was made to occlude the posterior choroidal feeding vessel with a large 25 mm × 50 cm coil, followed by a 6 mm × 20 cm coil; however, the high flow of the lesion displaced both coils into the wall of the aneurysmal venous sac. Interval magnetic resonance imaging and angiography revealed partial occlusion of the VoGM at 7 months and complete thrombosis at 24 months post procedure, precluding a need for additional coiling. This case illustrates that a minimal change in intramural flow dynamics of VoGMs could lead to progressive thrombosis.

Original languageEnglish (US)
Pages (from-to)296-298
Number of pages3
JournalWorld Neurosurgery
StatePublished - Aug 2018
Externally publishedYes


  • Complete occlusion
  • Single-stage transarterial venous sac embolization
  • Transarterial multistage embolization
  • Vein of Galen malformations

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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