Which patients need specific guidance? Part 2, chemoprophylaxis

Research output: Contribution to journalReview articlepeer-review


To prevent mosquito bites and thus reduce risk of malaria, dengue fever, and yellow fever in endemic areas, advise patients to apply an insect repellent containing deet (N,N-diethyl-3-methylbenzamide) to exposed skin and thin clothing, to sleep in well-screened or air-conditioned areas (or to sleep under a mosquito net pretreated with permethrin), and to wear long sleeves and trousers tucked into socks. Patients traveling to areas where chloroquine-sensitive malaria is endemic may take chloroquine as chemoprophylaxis. Those planning travel to areas with chloroquine-resistant malaria - except western Cambodia and the Thai-Myanmar and Thai-Cambodia border areas - may use mefloquine, doxycycline, or atovaquone/proguanil. Travelers to western Cambodia and the border areas mentioned above, where mefloquine- and chloroquine-resistant strains of malaria are present, can take doxycycline or atovaquone/proguanil. Chemoprophylaxis should be started 1 to 2 weeks before travel and continued for 4 weeks after return (7 days for atovaquone/proguanil). Key preventive measures for long-term travelers include vaccination against hepatitis A and B and malaria chemoprophylaxis.

Original languageEnglish (US)
Pages (from-to)1431-1437
Number of pages7
Issue number10
StatePublished - Sep 1 2001
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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