Alison J Kriegel

Research in Dr. Kriegel Lab is broadly focused on understanding how alterations in microRNAs (miRNAs), protein coding genes, and metabolites influence cardiovascular disease, cardiorenal syndrome, and renal disease. They utilize discovery-based approaches to studying these complex problems by blending next-generation technologies with molecular biology techniques, systems physiology, classical physiological studies, and translational research. Their current work is focused in three main areas: 1) determining mechanisms regulating declining renal function in hypertension, diabetes and CKD, 2) determining mechanisms regulating cardiovascular dysfunction in cardiorenal syndrome and during cancer treatment, and 3) understanding fundamental sex differences in renal and cardiovascular physiology and pathophysiology.