The pro-death protein MLKL regulates hematopoietic and non-hematopoietic pathways in atherosclerosis
- Katey K. Rayner(PI),
- Adil Rasheed(CoPI)
- University of Ottawa,
Grant:
Research project
Project status
Finished
About the Project
Coronary disease is caused by atherosclerosis, where immune cells build up in the artery wall in response to cholesterol and other inflammatory factors. How these immune cells are triggered and how they are activated is not well understood. This project will study a protein called MLKL to better understand how it controls the production of immune cells that worsen atherosclerosis.
Project Information
Project Type
Research project
Project Managed By
Time Period
04/01/2020 – 03/31/2025Status
FinishedFunding Details
The pro-death protein MLKL regulates hematopoietic and non-hematopoietic pathways in atherosclerosisAward
FunderAmount
Institute of Circulatory and Respiratory Health
589792 USD