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A deletion hybrid breakpoint map of the chromosomal region 13q14-q21 orders 19 genetic markers in 10 intervals

  • R. F. Kooy(corresponding author)
    ,
  • E. Verlind
    ,
  • R. H.J. Houwen
    ,
  • D. N. Shapiro
    ,
  • L. A. Hawthorn
    ,
*Corresponding author for this work
  • University of Groningen
Scholary Output:
Contribution to journal
Article
Peer-review

Abstract

A deletion hybrid breakpoint map of the chromosomal region 13q14-q21 has been constructed using 19 DNA markers and 13 cell lines with breakpoints in this chromosomal region. The cell lines define 10 distinct intervals in this region, which spans approximately 20 Mb. The markers include 6 RFLP markers, 11 microsatellites that provisionally had been mapped to the region 13q14-21, and 2 new polymorphic CA-repeats that were developed from an EMBL3 library of cell line ICD, containing 13pter-q14.3. The following order of markers was established: CEN - D13S320 - (D13S118, D13S153) - RB1- D13S319 - D13S25 - (D13S31, D13S59, D13S133, D13S137) - D13S163 - D13S119 - (D13S26, D13S55) - (D13S131, D13S134, D13S135, D13S144, D13S152) - TEL.

Publication Information

Output type

Scholary Output:
Contribution to journal
Article
Peer-review

Original language

English (US)

Pages from-to (Number of pages)

Pages 59-65 (7 pages)

Journal (Volume, Issue Number)

European Journal of Human Genetics (Volume 2, Issue 1)

Publication milestones

  • Published - 1994

Publication status

Published - 1994

ISSN

1018-4813

Publication IDs

  • Scopus: 0028274574
  • PubMed: 7913868

Publication metrics

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Scopus
citations
Fractional count
2
Fractional count
0.25
Fractional count
6
Fractional count
0.75
Fractional count
2
Fractional count
1

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