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Adjuvant bleomycin, etoposide and cisplatin in pathological stage II non-seminomatous testicular cancer. the Indiana University experience.

  • M Behnia
    ,
  • R Foster
    ,
  • L H Einhorn
    ,
  • J Donohue
    ,
  • C R Nichols
Scholary Output:
Contribution to journal
Article
 Peer-review

Open access

Sustainable Development Goals

  • SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well

Abstract

Two cycles of bleomycin, etoposide, and cisplatin (BEP) were evaluated as adjuvant chemotherapy for patients with pathological stage II non-seminomatous germ cell tumours. Between 1985 and 1995, 86 patients with pathological stage II non-seminomatous testicular cancer were treated with two cycles of BEP. At retroperitoneal lymph node dissection (RPLND) 49 patients (57%) had pathological stage II(A) (microscopic nodal metastases) and 37 (43%) had stage II(B) (gross nodal metastases). After RPLND, the patients received bleomycin, 30 units weekly for 8 weeks, etoposide (100 mg/m(2)) and cisplatin (20 mg/m(2)) each for 5 days every 28 days for two cycles as adjuvant chemotherapy. 4 patients were lost to follow-up. 10 patients (12%) developed granulocytopenic fever during their chemotherapy. Of the 82 evaluable patients all remained with no evidence of disease except for a single patient with a cervical nodal relapse of teratoma. This was resected and he remains disease free. Median follow

Publication Information

Output type

Scholary Output:
Contribution to journal
Article
 Peer-review

Original language

Undefined

Pages from-to (Number of pages)

Pages 472 - 475

Journal (Volume, Issue Number)

European Journal of Cancer (Volume 36, Issue 4)

Publication milestones

  • Published - 2000

Publication status

Published - 2000

ISSN

0959-8049

Publication IDs

  • Scopus: 0034012705
  • PubMed: 10717522

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Scopus
citations
62, opens in new tab
Fractional count
2
Fractional count
0.40
Fractional count
3
Fractional count
0.60
Fractional count
2
Fractional count
1
SciVal
citations
48
SciVal
FWCI
0.70
SciVal
Author count
5
SciVal
Paper percentile
84

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Captures
16
Citation count
61