Cancer stem cells: Nature versus nurture
- Hasan Korkaya(corresponding author),
- Max S. Wicha
- University of Michigan, Ann Arbor
Scholary Output:
Contribution to journal
Short survey
Peer-review
Open access
Sustainable Development Goals
SDG 3 Good Health and Well
Abstract
Although all cells within a colon cancer may harbour adenomatous polyposis coli (APC) or Β-catenin mutations, activation of Wnt signalling is limited to a subpopulation of cells that display cancer stem cell properties. This activation requires a co-stimulatory signal mediated by hepatocyte growth factor, which is produced by tumour-associated myofibroblasts.
Publication Information
Output type
Scholary Output:
Contribution to journal
Short survey
Peer-reviewOriginal language
English (US)Pages from-to (Number of pages)
Pages 419-421 (3 pages)Journal (Volume, Issue Number)
Nature Cell Biology (Volume 12, Issue 5)Publication milestones
- Published - 05/01/2010
Publication status
Published - 05/01/2010
ISSN
1465-7392Publication IDs
- Scopus: 77951975772
- PubMed: 20418873
Publication metrics
Metrics
SciVal
citations
39
SciVal
FWCI
2.05
SciVal
Author count
2
SciVal
Paper percentile
87
Fractional count
1
Fractional count
0.50
Fractional count
1
Fractional count
0.50
Fractional count
1
Fractional count
1
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Captures
129
Citation count
46