Characterization of the interaction between phthalocyanine and amyloid fibrils by surface-enhanced Raman scattering (SERS)
- Mykhaylo Yu Losytskyy(corresponding author),
- Nuriye Akbay,
- Svitlana Chernii,
- Ertug Avcı,
- Viktor Chernii,
- Sergiy Yarmoluk
- NASU - Institute of Molecular Biology and Genetics,
- Istanbul Medeniyet University,
- Yeditepe University,
- NASU - Vernadsky Institute General and Inorganic Chemistry
Scholary Output:
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Article
Peer-reviewAbstract
The applicability of surface-enhanced Raman scattering (SERS) on silver nanoparticles for characterization of interaction between the phthalocyanine molecule and amyloid fibril was studied using the axially coordinated Hf phthalocyanine dichloride and fibrils of amyloidogenic protein insulin. The SERS spectra of the phthalocyanine were obtained; the analytical enhancement factor was estimated to be in the range from 4 to 6 ×104. An intensity enhancement in its SERS spectra caused by the presence of fibrillar insulin was observed. Deviation of this enhancement with the change of fibrillar insulin concentration was manifested.
Publication Information
Output type
Scholary Output:
Contribution to journal
Article
Peer-reviewOriginal language
English (US)Pages from-to (Number of pages)
Pages 221-228 (8 pages)Journal (Volume, Issue Number)
Analytical Letters (Volume 51, Issue 1-2)Publication milestones
- Published - 10/28/2018
Publication status
Published - 10/28/2018
ISSN
0003-2719Publication IDs
- Scopus: 85032658495
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Funding Details
This work was supported by NASU-TUBITAK joint project 114Z464.
FunderFunding number
NASU-TUBITAK
114Z464