Conformationally assisted lactamizations for the synthesis of symmetrical and unsymmetrical bis-2,5-diketopiperazines
- Khanh Ha,
- Iryna Lebedyeva,
- Zhiliang Li,
- Kristin Martin,
- Byron Williams,
- Eric Faby
- University of Florida,
- University of Tartu,
- King Abdulaziz University
Scholary Output:
Contribution to journal
Article
Peer-reviewAbstract
Open-chain N-Cbz-protected-peptidoyl benzotriazolides are converted by a novel lactamization strategy using proline as a turn introducer into both symmetrical (5a-c and 11a-c) and unsymmetrical (19a-e) bis-2,5-diketopiperazines (bis-2,5-DKPs), previously recognized as difficult targets.
Publication Information
Output type
Scholary Output:
Contribution to journal
Article
Peer-reviewOriginal language
English (US)Pages from-to (Number of pages)
Pages 8510-8523 (14 pages)Journal (Volume, Issue Number)
Journal of Organic Chemistry (Volume 78, Issue 17)Publication milestones
- Published - 09/06/2013
Publication status
Published - 09/06/2013
ISSN
0022-3263Publication IDs
- Scopus: 84883754242
- PubMed: 23895184
Publication metrics
Metrics
SciVal
citations
5
SciVal
FWCI
0.50
SciVal
Author count
10
SciVal
Paper percentile
54
Fractional count
1
Fractional count
0.10
Fractional count
9
Fractional count
0.90
Fractional count
1
Fractional count
1
PlumX, opens in new tab
Captures
20
Citation count
7