Differential effects of left versus right seizure focus on human hippocampal evoked responses
- Kimford J. Meador(corresponding author),
- David W. Loring,
- Brian B. Gallagher,
- Don W. King,
- Anthony M Murro,
- Elaine E. Thompson
- Medical College of Georgia,
- ,
Scholary Output:
Contribution to journal
Article
Peer-reviewAbstract
Hippocampal evoked potentials were recorded using the P3 tonal oddball paradigm in 30 patients with unilateral temporal lobe seizure focus. Spectral power of the evoked potentials was decreased on the side of seizure focus, but this reduction was much greater when the focus was on the left. The effect of left/right focus does not appear to be due to group differences in age, sex, seizure duration, or operative pathology. Remote or finer left/right structural differences or differential left/right hippocampal processing for the sequential tonal task are possible explanations.
Publication Information
Output type
Scholary Output:
Contribution to journal
Article
Peer-reviewOriginal language
English (US)Pages from-to (Number of pages)
Pages 87-91 (5 pages)Journal (Volume, Issue Number)
International Journal of Neuroscience (Volume 66, Issue 1-2)Publication milestones
- Published - 1992
Publication status
Published - 1992
ISSN
0020-7454Publication IDs
- Scopus: 0026920852
- PubMed: 1304573
Publication metrics
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2
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0.18
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9
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0.82
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2
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1
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Funding Details
We thank K. Stanford and J. Jackson for technical assistance and P. Turner for typing the manuscript. The research was supported in part by NIH/NIA grant #KO8 AG00314. The study was presented in part at the 1990 annual meeting of the American Academy of Neurology, Miami, FL.
FundersFunding numbers
NIH/NIA
8 AG00314
NIA
K08AG000314