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Dosimetric Characterization of Photobiomodulation Devices at 660nm and 810nm for Clinical Applications in Dentistry

  • Dennis Sourvanos(corresponding author)
    ,
  • Timothy C. Zhu
    ,
  • Andreea Dimofte
    ,
  • Theresa M. Busch
    ,
  • Weibing Yang
    ,
  • Praveen Arany
*Corresponding author for this work
Scholary Output:
Chapter in Book/Report/Conference proceeding
Conference contribution

Related Event

Title

Mechanisms of Photobiomodulation Therapy XIX 2025

Event type

Conference

Date

01/25/2025 - 01/26/2025

Location

San FranciscoUnited States

Abstract

Photobiomodulation (PBM) uses red and near-infrared light (600-1, 100nm) as a noninvasive treatment in dentistry. Effective PBM therapy relies on understanding dosimetry variables like energy, focal spot size, irradiation, fluence rate, light distribution, and tissue interaction. This study evaluates FDA-approved PBM devices at 660nm and 810nm wavelengths, focusing on these parameters in clinical settings to enhance the effectiveness of PBM therapy and guide future protocols. Light distribution measurements were taken in a heterogeneous medium using an isotropic detector at distances from 0 to 30 mm. Both linear and nonlinear wavelength fitting algorithms assessed optical parameters, such as light absorption (µa), scattering (µ's), and effective attenuation (µ-eff). The fluence rate was calculated in mW/cm2, and data analysis will determine the mean and standard deviation for each wavelength. Results indicate marked differences in light distribution between 660nm and 810nm devices. Variations in fluence rates may affect tissue interaction and therapeutic outcomes. This study highlights the need for tailored device settings based on clinical context and target tissue to improve dental PBM protocols. Future research should link these dosimetry results with clinical outcomes for enhanced treatment precision.

Publication Information

Output type

Scholary Output:
Chapter in Book/Report/Conference proceeding
Conference contribution

Original language

English (US)

Article number

1329706

Publication milestones

  • Published - 2025

Publication status

Published - 2025

Publisher

SPIE, United States

Publication series

  • Publication series name: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
    ISSN (Print): 1605-7422
    Volume: 13297

ISBN (Electronic)

9781510683426

Publication IDs

  • Scopus: 105004267748

Host publication title

Mechanisms of Photobiomodulation Therapy XIX

Host publication editors

  • Ann Liebert
  • Jeri-Anne Lyons
  • James D. Carroll

Publication metrics

Metrics

Fractional count
1
Fractional count
0.11
Fractional count
8
Fractional count
0.89
Fractional count
1
Fractional count
1

Funding Details

DS was supported as an NIH NIDCR T90 Postdoctoral Fellow with the Center for Innovation and Precision Dentistry, Schools of Dental Medicine and Engineering, University of Pennsylvania (T90DE030854). DS is also supported by the American Dental Association Foundation Crest and Oral B Promising Researcher Award of 2023 and the American Association for Dental, Oral, and Craniofacial Research William B. Clark Fellowship in Periodontal Research. TZ is supported by US NIH funding mechanisms R01 EB029998 and R01 EB032821. TMB reports equity from Symphotek, Inc.
FundersFunding numbers
NIH
-
American Dental Association Council on Dental Practice
-
Center for Innovation and Precision Dentistry, Schools of Dental Medicine and Engineering, University of Pennsylvania
T90DE030854
American Association for Dental Research
R01 EB032821, R01 EB029998