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Fibrosing Mediastinitis in Pregnancy: A Rare Case With Antepartum Hemoptysis and Airway Obstruction

  • Poojita Chinmay(corresponding author)
    ,
  • Dhruti Trivedi
    ,
  • ,
  • K. M. Shaheen U Islam
    ,
  • Hamer M. Titus
    ,
  • Nikhil Madala
*Corresponding author for this work
Scholary Output:
Contribution to journal
Article
Peer-review

Open access

Abstract

Background: Fibrosing mediastinitis (FM) is a rare, progressive disorder characterized by dense fibrotic encasement of mediastinal structures, leading to airway and vascular compromise. Pregnancy-associated FM is exceptionally uncommon, with fewer than 2 dozen cases reported. Case Summary: We present a case of a 37-year-old woman, gravida 1 para 0, with known FM who developed antepartum hemoptysis and left lung atelectasis at 23 weeks of pregnancy. Computed tomography scan of the chest showed an 80% narrowing of the left main bronchus due to a calcified mediastinal mass. She was managed conservatively with nebulizers and physiotherapy, followed by bronchoscopy with balloon dilation of the left main bronchus. Delivery via classical cesarean at 24 weeks resulted in a viable neonate. Discussion: Physiologic changes during pregnancy can exacerbate cardiopulmonary compromise in FM, requiring multidisciplinary co-ordination. Take-Home Messages: FM may remain stable during pregnancy, and conservative management with close pulmonary and obstetric collaboration can achieve favorable outcomes. Further evaluation with a computed tomography chest scan may be required to assess the need for intervention when oxygenation and hemodynamic status are compromised.

Publication Information

Output type

Scholary Output:
Contribution to journal
Article
Peer-review

Original language

English (US)

Article number

106496

Journal (Volume, Issue Number)

JACC: Case Reports (Volume 31, Issue 13)

Publication milestones

  • Published - 04/01/2026

Publication status

Published - 04/01/2026

Publication IDs

  • Scopus: 105033488951

Publication metrics

Metrics

Fractional count
2
Fractional count
0.25
Fractional count
6
Fractional count
0.75
Fractional count
2
Fractional count
1

Funding Details

This study was supported by the Division of Cardiology Foundation Fund. The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
FunderFunding numbers
Division of Cardiology Foundation Fund
-