Gene expression profiling of Non-small cell lung cancer
- Sunil Singhal(corresponding author),
- ,
- Suresh Ramalingam,
- Shi Yong Sun
- Emory University
Open access
Sustainable Development Goals
SDG 3 Good Health and Well
Abstract
Functional genomics has emerged over the past 10 years as a novel technology to study genetic alterations. Gene expression arrays are one genomic technique employed to discover changes in the DNA expression that occur in neoplastic transformation. Microarrays have been applied to investigating lung cancer. Specific applications include discovering novel genetic changes that occur in lung tumors. Microarrays can also be applied to improve diagnosis, staging and discover prognostic markers. The eventual goal of this technology is to discover new markers for therapy and to customize therapy based on an individual tumor genetic composition. In this review, we present the current state of gene expression array technology in its application to lung cancer.
Publication Information
Output type
Original language
English (US)Pages from-to (Number of pages)
Pages 313-324 (12 pages)Journal (Volume, Issue Number)
Lung Cancer (Volume 60, Issue 3)Publication milestones
- Published - 06/2008
Publication status
ISSN
0169-5002Publication IDs
- Scopus: 44449164317
- PubMed: 18440087