Goodpasture's syndrome complicating henoch-schönlein purpura

Pulmonary hemorrhage in a patient with Henoch-Schönlein purpura was shown at autopsy to be caused most likely by Goodpasture's syndrome. The diagnosis was missed in part because of repeated negative assays for glomerular basement membrane antibodies. Linear fluorescence for immunoglobulin G was found in lung and glomeruli at postmortem. Development of Goodpasture's syndrome might be a result of release of glomerular basement membrane antigen by vasculitis.