Label-free ferrohydrodynamic cell separation of circulating tumor cells
- Wujun Zhao,
- Rui Cheng,
- Brittany D. Jenkins,
- Melissa B. Davis,
- ,
- Zhonglin Hao
- University of Georgia,
- ,
- Augusta University
Scholary Output:
Chapter in Book/Report/Conference proceeding
Conference contribution
Sustainable Development Goals
- SDG 3 Good Health and Well
Related Event
Title
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
Event type
ConferenceDate
10/22/2017 - 10/26/2017Location
SavannahUnited States
Abstract
We report a label-free ferrohydrodynamic cell separation (FCS) technology that is capable of high-throughput (6 mL/h), high recovery rate (92.9%), and biocompatible enrichment of circulating tumor cells (CTCs) from cancer patient blood, by systematically investigating the device operating parameters. We show cancer cells have excellent short-term viability, unaffected biomarker expressions, and ability to proliferate to confluence after FCS process. We apply FCS to successfully enrich CTCs from blood of non-small cell lung cancer (NSCLC) patients.
Publication Information
Output type
Scholary Output:
Chapter in Book/Report/Conference proceeding
Conference contribution
Original language
English (US)Pages from-to (Number of pages)
Pages 868-869 (2 pages)Publication milestones
- Published - 01/01/2020
Publication status
Published - 01/01/2020
Publisher
Chemical and Biological Microsystems SocietyPublication series
- Publication series name: 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
ISBN (Electronic)
9780692941836Host publication title
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017Access to documents
Publication metrics
Metrics
Fractional count
1
Fractional count
0.13
Fractional count
7
Fractional count
0.88
Fractional count
1
Fractional count
1
