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Label-free ferrohydrodynamic cell separation of circulating tumor cells

  • Wujun Zhao
    ,
  • Rui Cheng
    ,
  • Brittany D. Jenkins
    ,
  • Melissa B. Davis
    ,
  • ,
  • Zhonglin Hao
*Corresponding author for this work
  • University of Georgia
    ,
  • ,
  • Augusta University
Scholary Output:
Chapter in Book/Report/Conference proceeding
Conference contribution

Sustainable Development Goals

  • SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well

Related Event

Title

21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Event type

Conference

Date

10/22/2017 - 10/26/2017

Location

SavannahUnited States

Abstract

We report a label-free ferrohydrodynamic cell separation (FCS) technology that is capable of high-throughput (6 mL/h), high recovery rate (92.9%), and biocompatible enrichment of circulating tumor cells (CTCs) from cancer patient blood, by systematically investigating the device operating parameters. We show cancer cells have excellent short-term viability, unaffected biomarker expressions, and ability to proliferate to confluence after FCS process. We apply FCS to successfully enrich CTCs from blood of non-small cell lung cancer (NSCLC) patients.

Publication Information

Output type

Scholary Output:
Chapter in Book/Report/Conference proceeding
Conference contribution

Original language

English (US)

Pages from-to (Number of pages)

Pages 868-869 (2 pages)

Publication milestones

  • Published - 01/01/2020

Publication status

Published - 01/01/2020

Publisher

Chemical and Biological Microsystems Society

Publication series

  • Publication series name: 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

ISBN (Electronic)

9780692941836

Host publication title

21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

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