Mechanisms by which diabetes increases cardiovascular disease
- Christian A. Gleissner,
- Elena Galkina,
- Jerry L. Nadler,
- Klaus Ley(corresponding author)
- La Jolla Institute for Allergy and Immunology,
- University of Virginia,
- ,
- ,
Scholary Output:
Contribution to journal
Review article
Peer-review
Open access
Sustainable Development Goals
SDG 3 Good Health and Well
Abstract
Diabetes mellitus is one of the major risk factors for cardiovascular disease which is the leading cause of death in the United States. Increasing prevalence of diabetes and diabetic atherosclerosis makes identification of molecular mechanisms by which diabetes promotes atherogenesis an important task. Targeting common pathways may ameliorate both diseases. This review focuses on well-known as well as newly discovered mechanisms which may represent promising therapeutic targets.
Publication Information
Output type
Scholary Output:
Contribution to journal
Review article
Peer-reviewOriginal language
English (US)Pages from-to (Number of pages)
Pages 131-140 (10 pages)Journal (Volume, Issue Number)
Drug Discovery Today: Disease Mechanisms (Volume 4, Issue 3)Publication milestones
- Published - 09/2007
Publication status
Published - 09/2007
ISSN
1740-6765Publication IDs
- Scopus: 47049121292
Publication metrics
Metrics
Fractional count
1
Fractional count
0.25
Fractional count
3
Fractional count
0.75
Fractional count
1
Fractional count
1
PlumX, opens in new tab
Captures
149
Social media
2
Citation count
79
Funding Details
This work was supported by the Deutsche Forschungsgemeinschaft (grant GL599/1-1 to C.A.G.), by NIH grant HL58108 (to K.L.), and by NIH grant HL55798 (to K.L. and J.L.N.).
FundersFunding numbers
NIH
HL58108, HL55798
DFG
GL599/1-1