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Palladium-catalyzed N-arylation of 3-functionalized 2-amino-4,5- dimethylpyrroles

  • Carlos P. Griswold
    ,
  • Nisaraporn Suthiwangcharoen
    ,
  • Steven M. Pochini
    ,
  • Chad E. Stephens
  • Augusta University
Scholary Output:
Contribution to journal
Article
Peer-review

Open access

Abstract

A versatile class of 2-aminopyrroles containing various electron-withdrawing substituents at the 3-position have been N-arylated on the amine using a palladiumcatalyzed cross-coupling reaction. Using this methodology, a pyrimidone-based tricyclic system has been prepared in just one step from a starting 2-aminopyrrole.

Publication Information

Output type

Scholary Output:
Contribution to journal
Article
Peer-review

Original language

English (US)

Pages from-to (Number of pages)

Pages 1672-1681 (10 pages)

Journal (Volume, Issue Number)

Synthetic Communications (Volume 41, Issue 11)

Publication milestones

  • Published - 2011

Publication status

Published - 2011

ISSN

0039-7911

Publication IDs

  • Scopus: 79955681048

Publication metrics

Metrics

SciVal
citations
2
Fractional count
1
Fractional count
0.25
Fractional count
3
Fractional count
0.75
Fractional count
1
Fractional count
1
Scopus
citations
SciVal
FWCI
0.10
SciVal
Author count
4
SciVal
Paper percentile
40

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Citation count
3
Captures
4

Funding Details

We thank our department and the Pamplin College of Arts and Sciences for funding of this research.