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Qualitative analysis of a stochastic SEITR epidemic model with multiple stages of infection and treatment

*Corresponding author for this work
  • Marshall University
    ,
  • University of South Florida
Scholary Output:
Contribution to journal
Article
Peer-review

Open access

Sustainable Development Goals

  • SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well

Abstract

We present a mathematical analysis of the transmission of certain diseases using a stochastic susceptible-exposed-infectious-treated-recovered (SEITR) model with multiple stages of infection and treatment and explore the effects of treatments and external fluctuations in the transmission, treatment and recovery rates. We assume external fluctuations are caused by variability in the number of contacts between infected and susceptible individuals. It is shown that the expected number of secondary infections produced (in the absence of noise) reduces as treatment is introduced into the population. By defining RT,n and RT,n as the basic deterministic and stochastic reproduction numbers, respectively, in stage n of infection and treatment, we show mathematically that as the intensity of the noise in the transmission, treatment and recovery rates increases, the number of secondary cases of infection increases. The global stability of the disease-free and endemic equilibrium for the deterministic and stochastic SEITR models is also presented. The work presented is demonstrated using parameter values relevant to the transmission dynamics of Influenza in the United States from October 1, 2018 through May 4, 2019 influenza seasons.

Publication Information

Output type

Scholary Output:
Contribution to journal
Article
Peer-review

Original language

English (US)

Pages from-to (Number of pages)

Pages 61-90 (30 pages)

Journal (Volume, Issue Number)

Infectious Disease Modelling (Volume 5)

Publication milestones

  • Published - 2020

Publication status

Published - 2020

ISSN

2468-0427

Publication IDs

  • Scopus: 85078813589
  • ORCID: /0000-0002-8360-9094/work/107901105

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