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Reaction of barbituric acid with organic azides and phosphonium ylides

  • Iryna Oleksandrivna Lebedyeva
    ,
  • Sean M. Sileno
    ,
  • Kunal Patel
    ,
  • Ion Ghiviriga
    ,
  • Peter J. Steel
    ,
  • Alan R. Katritzky
  • University of Florida
    ,
  • University of Canterbury
    ,
  • King Abdulaziz University
Scholary Output:
Contribution to journal
Article
 Peer-review

Open access

Abstract

Amination by organic azides has been carried out to provide aminobarbiturates by fusion of a triazole ring to the 5,6-positions of barbituric acid followed by cleavage and thermal elimination of nitrogen, whereas aza-Wittig reaction gave phosphoranylidene barbituric acid salts.

Publication Information

Output type

Scholary Output:
Contribution to journal
Article
 Peer-review

Original language

English (US)

Pages from-to (Number of pages)

Pages 1019-1022 (4 pages)

Journal (Volume, Issue Number)

Central European Journal of Chemistry (Volume 11, Issue 6)

Publication milestones

  • Published - 2013

Publication status

Published - 2013

ISSN

1895-1066

Publication IDs

  • Scopus: 84894454280

Access to documents

Publication metrics

Metrics

SciVal
Author count
6
SciVal
Paper percentile
24
Fractional count
1
Fractional count
0.17
Fractional count
5
Fractional count
0.83
Fractional count
1
Fractional count
1

Funding Details

This work was supported by the Kenan Foundation (University of Florida) and the King Abdulaziz University (Saudi Arabia). The authors are grateful to Dr. C. D. Hall, Mrs. Galyna Vakulenko, Dr. Eric Scriven and Mr. Khanh Ha for reading the manuscript, and to Dr. M. C. A. Dancel (University of Florida) for HRMS analyses.
FundersFunding numbers
Kenan Foundation
-
UF
-
KAU
-