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Recovery of rat gastric mucosa following single fluoride dosing

  • R. P. Easmann
    ,
  • D. H. Pashley(corresponding author)
    ,
  • N. L. Birdsong
    ,
  • R. V. Mckinney
    ,
  • G. M. Whitford
*Corresponding author for this work
  • Medical College of Georgia
Scholary Output:
Contribution to journal
Article
Peer-review

Sustainable Development Goals

  • SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well

Abstract

Rats' stomachs were intubated with 0.1 N HCl or 100 mM NaF in 0.1 N HCl and excised after 1, 12, 24, 48 h or 7 days for light microscopy. The NaF solution caused erosive injury to the oxyntic glandular mucosa 1 h after application. Progressive stages of recovery were seen at 12, 24 and 48 h after fluoride dosing. Complete recovery was seen 7 days after exposure to fluoride. The kinetics of the recovery process from fluoride injury appear to he similar to those which have been reported for gastric injury produced by other substances.

Publication Information

Output type

Scholary Output:
Contribution to journal
Article
Peer-review

Original language

English (US)

Pages from-to (Number of pages)

Pages 779-792 (14 pages)

Journal (Volume, Issue Number)

Journal of Oral Pathology & Medicine (Volume 14, Issue 10)

Publication milestones

  • Published - 11/1985

Publication status

Published - 11/1985

ISSN

0904-2512

Publication IDs

  • Scopus: 0022397003
  • PubMed: 3932617

Publication metrics

Metrics

Scopus
citations
Fractional count
2
Fractional count
0.40
Fractional count
3
Fractional count
0.60
Fractional count
2
Fractional count
1

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Citation count
13