Regioselective synthesis and theoretical studies of an anti-neoplastic fluoro-substituted dispiro-oxindole
- Adel S. Girgis,
- ,
- Peter J. Steel
- University of Florida,
- National Research Center,
- Center for Heterocyclic Compounds,
- University of Canterbury
Scholary Output:
Contribution to journal
Article
Peer-reviewAbstract
Single crystal X-ray studies of regioselectively synthesized fluoro-substituted dispiro-oxindole 9 revealed that the structure belongs to the monoclinic space group P21/n with four molecules in the unit cell. The structure was also investigated by AM1, PM3, and DFT studies. Compound 9 exhibits high potency against the HeLa cell line.
Publication Information
Output type
Scholary Output:
Contribution to journal
Article
Peer-reviewOriginal language
English (US)Pages from-to (Number of pages)
Pages 14780-14787 (8 pages)Journal (Volume, Issue Number)
RSC Advances (Volume 5, Issue 19)Publication milestones
- Published - 2015
Publication status
Published - 2015
ISSN
2046-2069Publication IDs
- Scopus: 84922625304
- ORCID: /0000-0003-3668-104X/work/67684029
Publication metrics
Metrics
Fractional count
1
Fractional count
0.33
Fractional count
2
Fractional count
0.67
Fractional count
1
Fractional count
1
SciVal
citations
21
SciVal
FWCI
1.89
SciVal
Author count
7
SciVal
Paper percentile
83
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Citation count
28
Captures
4