Synthesis of l-lys-aminoxy-goralatide
- Zhiliang Li(corresponding author),
- Iryna Oleksandrivna Lebedyeva,
- Deqian Zhao,
- Lauren Myers,
- Girinath G. Pillai,
- Charles Dennis Hall
- University of Florida
Scholary Output:
Contribution to journal
Article
Peer-reviewAbstract
Natural tetrapeptide Goralatide inhibits primitive hematopoietic cell proliferation but reported to be rather unstable in solution (half-life 4.5 min). In this work, we report the synthesis of an aminoxy analog of Goralatide. Aminoxy moiety is expected to provide increased stability and bioavailability of the Goralatide analog.
Publication Information
Output type
Scholary Output:
Contribution to journal
Article
Peer-reviewOriginal language
English (US)Pages from-to (Number of pages)
Pages 923-927 (5 pages)Journal (Volume, Issue Number)
Journal of Peptide Science (Volume 20, Issue 12)Publication milestones
- Published - 10/20/2014
Publication status
Published - 10/20/2014
ISSN
1075-2617Publication IDs
- Scopus: 84918830119
- PubMed: 25331328
Publication metrics
Metrics
SciVal
Author count
7
SciVal
Paper percentile
24
Fractional count
1
Fractional count
0.14
Fractional count
6
Fractional count
0.86
Fractional count
1
Fractional count
1
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Captures
4
Citation count
1