The cross-reactive idiotype of A-strain mice Serological and structural analyses

Idiolypes have been implicated in the induction and regulation of complex humoral and cell-mediated immune phenomena. Now, with the development of hybridoma technology, the enigma of the molecular basis of idiotypy is succumbing to systematic serological and structural analyses. Here Don Capra and his colleagues describe recent studies on one of the best known idiotype .systems, in the antibody response to arsonate.