Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells
- Ying Jiang,
- Qian Ding,
- ,
- Richard T. Libby,
- Veronique Lefebvre,
- Lin Gan(corresponding author)
- University of Rochester,
- Cleveland Clinic Foundation,
- Hangzhou Normal University
Scholary Output:
Contribution to journal
Article
Peer-reviewAbstract
Background: Roles of SoxC genes in the development of retinal ganglion cells (RGCs) are unknown at present. Results: Targeted deletion of Sox4 and Sox11 in retina results in a complete loss of RGCs. Conclusion: Sox4 and Sox11 function redundantly to regulate RGC development. Significance: These findings highlight the essential role of SoxC genes in retinal development.
Publication Information
Output type
Scholary Output:
Contribution to journal
Article
Peer-reviewOriginal language
English (US)Pages from-to (Number of pages)
Pages 18429-18438 (10 pages)Journal (Volume, Issue Number)
Journal of Biological Chemistry (Volume 288, Issue 25)Publication milestones
- Published - 06/21/2013
Publication status
Published - 06/21/2013
ISSN
0021-9258Publication IDs
- Scopus: 84880068310
- PubMed: 23649630
- ORCID: /0000-0001-6764-1185/work/68887605
Publication metrics
Metrics
SciVal
FWCI
2.24
SciVal
Author count
6
SciVal
citations
71
SciVal
Paper percentile
96
SciVal
Top percentile
5
Fractional count
2
Fractional count
0.33
Fractional count
4
Fractional count
0.67
Fractional count
2
Fractional count
1
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Citation count
105
Captures
83
Funding Details
FundersFunding numbers
NIAMS
R01AR054153
NCATS
UL1TR000439