True one cell chemical analysis: A review
- Imesha W. De Silva,
- Amanda R. Kretsch,
- Holly May Lewis,
- Melanie Bailey,
- Guido F. Verbeck(corresponding author)
- University of North Texas,
- University of Surrey
Scholary Output:
Contribution to journal
Article
Peer-reviewAbstract
The constantly growing field of True One Cell (TOC) analysis has provided important information on the direct chemical composition of various cells and cellular components. Since the heterogeneity of individual cells has been established, more researchers are interested in the chemical differences between individual cells; TOC is the only form of analysis that can provide this information. This has resulted in the constant development of new technologies and methods. This review highlights the common techniques for micro- and nanomanipulation, Raman spectroscopy, microscopy, and mass spectrometric imaging as they pertain to TOC chemical analysis.
Publication Information
Output type
Scholary Output:
Contribution to journal
Article
Peer-reviewOriginal language
English (US)Pages from-to (Number of pages)
Pages 4733-4749 (17 pages)Journal (Volume, Issue Number)
Analyst (Volume 144, Issue 16)Publication milestones
- Published - 08/21/2019
Publication status
Published - 08/21/2019
ISSN
0003-2654Publication IDs
- Scopus: 85070247160
- PubMed: 31199412
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1
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4
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0.80
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1
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1
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31
Citation count
9
Funding Details
Melanie Bailey is a Senior Lecturer in Analytical and Forensic Science at the University of Surrey. She has recently been awarded a five-year fellowship from the Electronics and Physical Sciences Research Council, which is exploring spatially resolved mass spec trometry and ion beam analysis (for high resolution elemental mapping).
FundersFunding number
Electronics and Physical Sciences Research Council
-EPSRC
EP/P001440/1