Projects per year
Organization profile
Organization profile
Collaborative Publications from two or more individuals with TRIBA interests
As people get older, they experience a low-level of inflammation, described as “inflammaging,” driven by an increase in molecules in the blood called cytokines. This age-related inflammation has been linked to serious chronic diseases, including Alzheimer’s disease, cardiovascular disease, atherosclerosis, type II diabetes and cancer. The main feature of the aging process is chronic and progressive inflammation, which is a significant risk factor in morbidity and mortality. While most age-related diseases include inflammation, its potential cause and role in adverse health outcomes is still widely unknown.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Dive into the research topics where Transdisciplinary Research Initiative in Inflammaging and Brain Aging (TRIBA) is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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PROJECT 2 - Kyn-AhR interactions modulating muscle-bone crosstalk with aging
Hamrick, M. M. W. (PI) & Hamrick, M. W. (PI)
6/1/23 → 5/31/25
Project: Research project
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PROJECT 3 - Kynurenine-AhR Signaling Effects on Mitophagy and Senescence with Age in Bone Marrow Stem Cells
Fulzele, S. T. (PI)
6/1/23 → 5/31/25
Project: Research project
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Novel mechanisms of muscle and bone loss with HIV infection, antiretroviral therapy, and aging.
Mcgee-lawrence, M. M. E. (PI), Belin de Chantemele, E. J. (CoPI) & Hamrick, M. W. (CoPI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
4/1/23 → 3/31/26
Project: Research project
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Acute-Phase Recording of the Spreading Depolarization Continuum in Aged Nonhuman Primates during Focal Ischemic Stroke
Sword, J. J., Sparks, T., Debs, L. H., Major, S., Sharma, S. J., Jensen, M. A., Moore-Hill, D. T., Barton, K., Shah, M., Garcia, K. A., Switzer, J. A., Blake, D. T., Vale, F. L., Dreier, J. P., Hartings, J. A. & Kirov, S. A., Apr 1 2025, In: Stroke. 56, 4, p. 974-986 13 p.Research output: Contribution to journal › Article › peer-review
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Basal forebrain activation improves working memory in senescent monkeys
Pennington, K. R., Debs, L., Chung, S., Bava, J., Garin, C. M., Vale, F. L., Bick, S. K., Englot, D. J., Terry, A. V., Constantinidis, C. & Blake, D. T., Mar 1 2025, In: Brain Stimulation. 18, 2, p. 185-194 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Gut microbiota dysbiosis in Alzheimer's disease (AD): Insights from human clinical studies and the mouse AD models
Manfredi, J. N., Gupta, S. K., Vyavahare, S., Deak, F., Lu, X., Buddha, L., Wankhade, U., Lohakare, J., Isales, C. & Fulzele, S., Mar 1 2025, In: Physiology and Behavior. 290, 114778.Research output: Contribution to journal › Review article › peer-review