Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Targeting the core components of the Hsp90 chaperoning machine
Chadli, A. & CHADLI, A.
Project: Research project
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Targeting the core components of the Hsp90 chaperoning machine
Chadli, A., CHADLI, A., CHADLI, A. & CHADLI, A.
National Institute of General Medical Sciences
7/15/12 → 4/30/16
Project: Research project
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Stress biology: Complexity and multifariousness in health and disease
Mayer, M. P., Blair, L., Blatch, G. L., Borges, T. J., Chadli, A., Chiosis, G., de Thonel, A., Dinkova-Kostova, A., Ecroyd, H., Edkins, A. L., Eguchi, T., Fleshner, M., Foley, K. P., Fragkostefanakis, S., Gestwicki, J., Goloubinoff, P., Heritz, J. A., Heske, C. M., Hibshman, J. D., Joutsen, J., & 18 others , Feb 2024, In: Cell Stress and Chaperones. 29, 1, p. 143-157 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Capsaicin binds the N-terminus of Hsp90, induces lysosomal degradation of Hsp70, and enhances the anti-tumor effects of 17-AAG (Tanespimycin)
Patwardhan, C. A., Kommalapati, V. K., Llbiyi, T., Singh, D., Alfa, E., Horuzsko, A., Korkaya, H., Panda, S., Reilly, C. A., Popik, V. & Chadli, A., Dec 2023, In: Scientific reports. 13, 1, 13790.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Enniatin A Analogues as Novel Hsp90 Inhibitors that Modulate Triple-Negative Breast Cancer
Serwetnyk, M. A., Crowley, V. M., Brackett, C. M., Carter, T. R., Elahi, A., Kommalapati, V. K., Chadli, A. & Blagg, B. S. J., Dec 14 2023, In: ACS Medicinal Chemistry Letters. 14, 12, p. 1785-1790 6 p.Research output: Contribution to journal › Article › peer-review
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Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
Eisa, N. H., Crowley, V. M., Elahi, A., Kommalapati, V. K., Serwetnyk, M. A., Llbiyi, T., Lu, S., Kainth, K., Jilani, Y., Marasco, D., El Andaloussi, A., Lee, S., Tsai, F. T. F., Rodriguez, P. C., Munn, D., Celis, E., Korkaya, H., Debbab, A., Blagg, B. & Chadli, A., Dec 15 2023, In: iScience. 26, 12, 108308.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti–PD-1 resistance
Ajith, A., Mamouni, K., Horuzsko, D. D., Musa, A., Dzutsev, A. K., Fang, J. R., Chadli, A., Zhu, X., Lebedyeva, I. O., Trinchieri, G. & Horuzsko, A., Nov 1 2023, In: Journal of Clinical Investigation. 133, 21, e167951.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations