Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Waaqo Boru Daddacha is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Mechanistic Interplays between cPP Tract and RT Inhibitor Sensitivity of HIV-1
Daddacha, W. B. (PI), DADDACHA, W. B. (PI) & DADDACHA, W. B. (PI)
Project: Research project
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Understanding mechanistic role of SAMHD1 in DNA damage response and therapeutic benefit for malignant glioma
Daddacha, W. B. (PI)
4/1/18 → 3/31/23
Project: Research project
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Functions of SAMHD1 in DNA Double-strand Break Repair
Daddacha, W. B. (PI)
National Institute of General Medical Sciences
9/1/16 → 8/31/17
Project: Research project
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SAMHD1 expression contributes to doxorubicin resistance and predicts survival outcomes in diffuse large B-cell lymphoma patients
Daddacha, W., Monroe, D., Schlafstein, A. J., Withers, A. E., Thompson, E. B., Danelia, D., Luong, N. C., Sesay, F., Rath, S. K., Usoro, E. R., Essien, M. E., Jung, A. T., Jiang, J. G., Hu, J., Mahboubi, B., Williams, A., Steinbeck, J. E., Yang, X., Buchwald, Z. S. & Dynan, W. S. & 5 others, , Mar 1 2024, In: NAR Cancer. 6, 1, zcae007.Research output: Contribution to journal › Article › peer-review
Open Access -
DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining
Head, P. S. E., Kapoor-Vazirani, P., Nagaraju, G. P., Zhang, H., Rath, S. K., Luong, N. C., Haji-Seyed-Javadi, R., Sesay, F., Wang, S. Y., Duong, D. M., Daddacha, W., Minten, E. V., Song, B., Danelia, D., Liu, X., Li, S., Ortlund, E. A., Seyfried, N. T., Smalley, D. M. & Wang, Y. & 5 others, , Aug 25 2023, In: Nucleic Acids Research. 51, 15, p. 7972-7987 16 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks
Kapoor-Vazirani, P., Rath, S. K., Liu, X., Shu, Z., Bowen, N. E., Chen, Y., Haji-Seyed-Javadi, R., Daddacha, W., Minten, E. V., Danelia, D., Farchi, D., Duong, D. M., Seyfried, N. T., Deng, X., Ortlund, E. A., Kim, B. & Yu, D. S., Dec 2022, In: Nature communications. 13, 1, 6707.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Viral Particle-Mediated SAMHD1 Depletion Sensitizes Refractory Glioblastoma to DNA-Damaging Therapeutics by Impairing Homologous Recombination
Daddacha, W., Monroe, D., Carver, K., Usoro, E. R., Alptekin, A., Xu, H., Osuka, S., Arbab, A. S. & Sakamuro, D., Sep 2022, In: Cancers. 14, 18, 4490.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Vectors in gene therapy: Benefit for glioblastoma patients
Carver, K., Negrete, D., Waterman, M. K. & Daddacha, W., Jan 1 2021, New Targeting in the Reversal of Resistant Glioblastomas. Elsevier, p. 161-176 16 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations