TY - JOUR
T1 - A tale of two vulvar angiomyxomas
T2 - Two cases and review of literature
AU - Navitski, Anastasia
AU - Adams, Leslie
AU - Brzezinska, Bogna N.
AU - Suhner, Jessa
AU - Sliker, Taylor
AU - Moideen, Pramila
AU - Barrett, Amanda
AU - Abualruz, Abdul R.
AU - Johnson, Marian S.
AU - Rungruang, Bunja
N1 - Publisher Copyright:
© 2023
PY - 2023/6
Y1 - 2023/6
N2 - Vulvar angiomyxomas are rare benign mesenchymal neoplasms. Superficial and Aggressive angiomyxomas are two distinct phenotypes that present similarly to other more common vulva-perineal pathologies. Albeit both angiomyxomas carry a risk of recurrence, especially in the setting of incomplete resection, simple excision is insufficient for Aggressive angiomyxoma. It requires wide local excision because of its unique potential for local invasion, infiltration of the paravaginal and pararectal tissue, and more distant metastasis. Here, we present a case of Superficial angiomyxoma and a case of Aggressive angiomyxoma to highlight the diagnostic challenges and management strategies of each tumor. In both cases, angiomyxomas were initially misdiagnosed because of their rarity and nonspecific presentation. Magnetic resonance imaging is the modality of choice for evaluation due to inherent higher spatial resolution of soft tissue anatomical details. Early diagnosis of Aggressive angiomyxoma can prevent incomplete excision and recurrence, spare additional surgery, and offer hormonal therapy options.
AB - Vulvar angiomyxomas are rare benign mesenchymal neoplasms. Superficial and Aggressive angiomyxomas are two distinct phenotypes that present similarly to other more common vulva-perineal pathologies. Albeit both angiomyxomas carry a risk of recurrence, especially in the setting of incomplete resection, simple excision is insufficient for Aggressive angiomyxoma. It requires wide local excision because of its unique potential for local invasion, infiltration of the paravaginal and pararectal tissue, and more distant metastasis. Here, we present a case of Superficial angiomyxoma and a case of Aggressive angiomyxoma to highlight the diagnostic challenges and management strategies of each tumor. In both cases, angiomyxomas were initially misdiagnosed because of their rarity and nonspecific presentation. Magnetic resonance imaging is the modality of choice for evaluation due to inherent higher spatial resolution of soft tissue anatomical details. Early diagnosis of Aggressive angiomyxoma can prevent incomplete excision and recurrence, spare additional surgery, and offer hormonal therapy options.
KW - Aggressive angiomyxoma
KW - Lower genital tract disease
KW - Superficial angiomyxoma
KW - Vulva
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U2 - 10.1016/j.gore.2023.101204
DO - 10.1016/j.gore.2023.101204
M3 - Article
AN - SCOPUS:85160787943
SN - 2211-338X
VL - 47
JO - Gynecologic Oncology Reports
JF - Gynecologic Oncology Reports
M1 - 101204
ER -