Ability of new obturation materials to improve the seal of the root canal system: A review

Guo Hua Li, Li Na Niu, Wei Zhang, Mark Olsen, Gustavo De-Deus, Ashraf A. Eid, Ji Hua Chen, David Henry Pashley, Franklin Chi Meng Tay

Research output: Contribution to journalReview articlepeer-review

86 Scopus citations


New obturation biomaterials have been introduced over the past decade to improve the seal of the root canal system. However, it is not clear whether they have really produced a three-dimensional impervious seal that is important for reducing diseases associated with root canal treatment. A review of the literature was performed to identify models that have been employed for evaluating the seal of the root canal system. In vitro and in vivo models are not totally adept at quantifying the seal of root canals obturated with classic materials. Thus, one has to resort to clinical outcomes to examine whether there are real benefits associated with the use of recently introduced materials for obturating root canals. However, there is no simple answer because endodontic treatment outcomes are influenced by a host of other predictors that are more likely to take precedence over the influence of obturation materials. From the perspective of clinical performance, classic root filling materials have stood the test of time. Because many of the recently introduced materials are so new, there is not enough evidence yet to support their ability to improve clinical performance. This emphasizes the need to translate anecdotal information into clinically relevant research data on new biomaterials.

Original languageEnglish (US)
Pages (from-to)1050-1063
Number of pages14
JournalActa biomaterialia
Issue number3
StatePublished - Mar 2014


  • Leakage models
  • Root canal
  • Root filling materials
  • Sealability
  • Treatment outcome

ASJC Scopus subject areas

  • Biotechnology
  • Biomaterials
  • Biochemistry
  • Biomedical Engineering
  • Molecular Biology


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