TY - JOUR
T1 - Advanced molecular imaging in large-vessel vasculitis
T2 - Adopting FDG-PET into a clinical workflow
AU - Ahlman, Mark A.
AU - Grayson, Peter C.
N1 - Publisher Copyright:
© 2023
PY - 2023/3
Y1 - 2023/3
N2 - The use of fluorodeoxyglucose–positron emission tomography (FDG-PET) imaging to detect vascular inflammation is increasingly common in the clinical management of patients with large-vessel vasculitis (LVV). In this review, the role of FDG-PET imaging to diagnose and monitor vascular disease activity will be detailed. Suggestions on incorporation of FDG-PET imaging into a clinical workflow will be provided with emphasis on patient preparation, image acquisition, and image interpretation. If FDG-PET imaging is obtained, multimodal imaging assessment, whereby FDG-PET imaging and non-invasive angiography are obtained concurrently, and correlation of imaging findings with clinical assessment is generally advisable. Considering the clinical scenario and treatment status of the patient is important when interpreting vascular FDG-PET image findings.
AB - The use of fluorodeoxyglucose–positron emission tomography (FDG-PET) imaging to detect vascular inflammation is increasingly common in the clinical management of patients with large-vessel vasculitis (LVV). In this review, the role of FDG-PET imaging to diagnose and monitor vascular disease activity will be detailed. Suggestions on incorporation of FDG-PET imaging into a clinical workflow will be provided with emphasis on patient preparation, image acquisition, and image interpretation. If FDG-PET imaging is obtained, multimodal imaging assessment, whereby FDG-PET imaging and non-invasive angiography are obtained concurrently, and correlation of imaging findings with clinical assessment is generally advisable. Considering the clinical scenario and treatment status of the patient is important when interpreting vascular FDG-PET image findings.
KW - Fluorodeoxyglucose
KW - Giant cell arteritis
KW - Imaging
KW - Large-vessel vasculitis
KW - PET-CT
KW - Takayasu's arteritis
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U2 - 10.1016/j.berh.2023.101856
DO - 10.1016/j.berh.2023.101856
M3 - Review article
C2 - 37516606
AN - SCOPUS:85172171078
SN - 1521-6942
VL - 37
JO - Best Practice and Research: Clinical Rheumatology
JF - Best Practice and Research: Clinical Rheumatology
IS - 1
M1 - 101856
ER -