Abstract
We investigated the relationship of amobarbital dosage to Wada memory performance in 72 patients who have subsequently undergone unilateral anterior temporal lobectomy (left, 39; right, 33). Significantly poorer recognition memory performance following injection ipsilateral to the seizure focus was associated with higher amobarbital dosage administration (r = -0.40; p <0.001). Patients were also dichotomized into "low" (125 mg and lower) and "high" (greater than 125 mg) dosage groups based on ipsilateral dosage, and significantly poorer recognition memory performance (p < 0.001) was observed following higher amobarbital administration. These data demonstrate that amobarbital dosage is one factor that contributes to memory performance during the Wada test.
Original language | English (US) |
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Pages (from-to) | 171-174 |
Number of pages | 4 |
Journal | Journal of Epilepsy |
Volume | 5 |
Issue number | 3 |
DOIs | |
State | Published - 1992 |
Keywords
- Amobarbital
- Epilepsy
- Memory
- Temporal lobectomy
- Wada test
ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Neurology