Anticoagulation in prosthetic valve endocarditis

John L. Carpenter, C. Kenneth McAllister, John Boslego, Joel Brown, John L. Carpenter, Ray Chung, Ronald Cooper, D. Baxter Craig, Alan Cross, David Haburchak, Shannon Harrison, Charles Hoke, Bruce McClain, Debra Omori, Steven Opal, Robert Redfield, Gerald Sadoff, Edmund Tramont

Research output: Contribution to journalArticlepeer-review

57 Scopus citations


We reviewed the experience with infective endocarditis at some major US Army Medical Centers. One hundred patients were studied, comparing 82 patients who had native valve endocarditis (NVE) with 18 patients who had prosthetic valve endocarditis (PVE). Among patients with PVE, four had porcine valves and 14 had synthetic. None of the patients with NVE had received anticoagulants; 14 of 18 patients with PVE had received anticoagulants. The major causes of death were central nervous system hemorrhage, congestive heart failure, uncontrolled infection, and embolic phenomena. The principal cause of death in patients with PVE was CNS hemorrhage. Of the patients with PVE, 36% had symptomatic cerebral hemorrhage while receiving anticoagulants and 80% of them died.

Original languageEnglish (US)
Pages (from-to)1372-1375
Number of pages4
JournalSouthern medical journal
Issue number11
StatePublished - Nov 1983
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Anticoagulation in prosthetic valve endocarditis'. Together they form a unique fingerprint.

Cite this