Anticoagulation in prosthetic valve endocarditis

John L. Carpenter; C. Kenneth McAllister; John Boslego; Joel Brown; John L. Carpenter; Ray Chung; Ronald Cooper; D. Baxter Craig; Alan Cross; David Haburchak; Shannon Harrison; Charles Hoke; Bruce McClain; Debra Omori; Steven Opal; Robert Redfield; Gerald Sadoff; Edmund Tramont

doi:10.1097/00007611-198311000-00011

Anticoagulation in prosthetic valve endocarditis

John L. Carpenter, C. Kenneth McAllister, John Boslego, Joel Brown, John L. Carpenter, Ray Chung, Ronald Cooper, D. Baxter Craig, Alan Cross, David Haburchak, Shannon Harrison, Charles Hoke, Bruce McClain, Debra Omori, Steven Opal, Robert Redfield, Gerald Sadoff, Edmund Tramont

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

We reviewed the experience with infective endocarditis at some major US Army Medical Centers. One hundred patients were studied, comparing 82 patients who had native valve endocarditis (NVE) with 18 patients who had prosthetic valve endocarditis (PVE). Among patients with PVE, four had porcine valves and 14 had synthetic. None of the patients with NVE had received anticoagulants; 14 of 18 patients with PVE had received anticoagulants. The major causes of death were central nervous system hemorrhage, congestive heart failure, uncontrolled infection, and embolic phenomena. The principal cause of death in patients with PVE was CNS hemorrhage. Of the patients with PVE, 36% had symptomatic cerebral hemorrhage while receiving anticoagulants and 80% of them died.

Original language	English (US)
Pages (from-to)	1372-1375
Number of pages	4
Journal	Southern medical journal
Volume	76
Issue number	11
DOIs	https://doi.org/10.1097/00007611-198311000-00011
State	Published - Nov 1983
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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10.1097/00007611-198311000-00011

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Carpenter, J. L., McAllister, C. K., Boslego, J., Brown, J., Carpenter, J. L., Chung, R., Cooper, R., Baxter Craig, D., Cross, A., Haburchak, D., Harrison, S., Hoke, C., McClain, B., Omori, D., Opal, S., Redfield, R., Sadoff, G., & Tramont, E. (1983). Anticoagulation in prosthetic valve endocarditis. Southern medical journal, 76(11), 1372-1375. https://doi.org/10.1097/00007611-198311000-00011

Carpenter, JL, McAllister, CK, Boslego, J, Brown, J, Carpenter, JL, Chung, R, Cooper, R, Baxter Craig, D, Cross, A, Haburchak, D, Harrison, S, Hoke, C, McClain, B, Omori, D, Opal, S, Redfield, R, Sadoff, G & Tramont, E 1983, 'Anticoagulation in prosthetic valve endocarditis', Southern medical journal, vol. 76, no. 11, pp. 1372-1375. https://doi.org/10.1097/00007611-198311000-00011

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title = "Anticoagulation in prosthetic valve endocarditis",

abstract = "We reviewed the experience with infective endocarditis at some major US Army Medical Centers. One hundred patients were studied, comparing 82 patients who had native valve endocarditis (NVE) with 18 patients who had prosthetic valve endocarditis (PVE). Among patients with PVE, four had porcine valves and 14 had synthetic. None of the patients with NVE had received anticoagulants; 14 of 18 patients with PVE had received anticoagulants. The major causes of death were central nervous system hemorrhage, congestive heart failure, uncontrolled infection, and embolic phenomena. The principal cause of death in patients with PVE was CNS hemorrhage. Of the patients with PVE, 36% had symptomatic cerebral hemorrhage while receiving anticoagulants and 80% of them died.",

author = "Carpenter, {John L.} and McAllister, {C. Kenneth} and John Boslego and Joel Brown and Carpenter, {John L.} and Ray Chung and Ronald Cooper and {Baxter Craig}, D. and Alan Cross and David Haburchak and Shannon Harrison and Charles Hoke and Bruce McClain and Debra Omori and Steven Opal and Robert Redfield and Gerald Sadoff and Edmund Tramont",

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doi = "10.1097/00007611-198311000-00011",

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AU - Carpenter, John L.

AU - McAllister, C. Kenneth

AU - Boslego, John

AU - Brown, Joel

AU - Carpenter, John L.

AU - Chung, Ray

AU - Cooper, Ronald

AU - Baxter Craig, D.

AU - Cross, Alan

AU - Haburchak, David

AU - Harrison, Shannon

AU - Hoke, Charles

AU - McClain, Bruce

AU - Omori, Debra

AU - Opal, Steven

AU - Redfield, Robert

AU - Sadoff, Gerald

AU - Tramont, Edmund

PY - 1983/11

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N2 - We reviewed the experience with infective endocarditis at some major US Army Medical Centers. One hundred patients were studied, comparing 82 patients who had native valve endocarditis (NVE) with 18 patients who had prosthetic valve endocarditis (PVE). Among patients with PVE, four had porcine valves and 14 had synthetic. None of the patients with NVE had received anticoagulants; 14 of 18 patients with PVE had received anticoagulants. The major causes of death were central nervous system hemorrhage, congestive heart failure, uncontrolled infection, and embolic phenomena. The principal cause of death in patients with PVE was CNS hemorrhage. Of the patients with PVE, 36% had symptomatic cerebral hemorrhage while receiving anticoagulants and 80% of them died.

AB - We reviewed the experience with infective endocarditis at some major US Army Medical Centers. One hundred patients were studied, comparing 82 patients who had native valve endocarditis (NVE) with 18 patients who had prosthetic valve endocarditis (PVE). Among patients with PVE, four had porcine valves and 14 had synthetic. None of the patients with NVE had received anticoagulants; 14 of 18 patients with PVE had received anticoagulants. The major causes of death were central nervous system hemorrhage, congestive heart failure, uncontrolled infection, and embolic phenomena. The principal cause of death in patients with PVE was CNS hemorrhage. Of the patients with PVE, 36% had symptomatic cerebral hemorrhage while receiving anticoagulants and 80% of them died.

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Anticoagulation in prosthetic valve endocarditis

Abstract

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