Autonomic Dysfunction and Adrenocortical Unresponsiveness to ACTH

George Makari, William H. Hoffman, James Edwin Carroll, Diane R. Savage, Theodora Van Der Zalm

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


A child is reported with adrenocortical unresponsiveness to ACTH and autonomic dysfunction. The latter consisted of cold extremities, progressive loss of tear production, the development of achalasia of the esophagus, pupillary dysfunction, and an abnormal histamine skin test. These findings suggest progressive parasympathetic denervation as a cause for the adrenocortical abnormality. (J Child Neurol 1988;3:174-176).

Original languageEnglish (US)
Pages (from-to)174-176
Number of pages3
JournalJournal of Child Neurology
Issue number3
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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