Basal metabolic rate in women with PCOS compared to eumenorrheic controls

Sara J. Churchill, Erica T. Wang, Gaisu Bhasin, Carolyn Alexander, Catherine Bresee, Marita Pall, Ricardo Azziz, Ruchi Mathur, Margareta D. Pisarska

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Objective PCOS is associated with obesity and insulin resistance. Efforts have focused on whether an abnormal energy homeostasis contributes to the development of obesity in these patients. There are conflicting results in the literature regarding whether women with PCOS have an altered basal metabolic rate (BMR), thereby leading to difficulties in weight loss. The objective of this study is to compare basal metabolic rate (BMR) in women with PCOS and controls. Design Cross-sectional study. Patients One hundred and twenty-eight PCOS patients diagnosed by original NIH consensus criteria and 72 eumenorrheic, non-hirsute controls were recruited from an academic medical centre. Measurements Assessment of BMR using the InBody portable bioelectrical impedance analysis (BIA) device and insulin resistance by HOMA-IR indices. Results PCOS women were younger than controls. As expected, PCOS subjects had higher body mass index (BMI), serum androgens and estimated insulin resistance. After adjusting for age and BMI, there was no significant difference in BMR between PCOS subjects (adjusted mean 5807 kJ/day, 95% CI 5715-5899) and controls (adjusted mean 5916 kJ/day, 95% CI 5786-6046) (P = 0·193). BMR was also comparable in a secondary analysis comparing PCOS women with and without insulin resistance. Conclusions After adjusting for age and BMI, there was no difference in BMR between PCOS women and controls.

Original languageEnglish (US)
Pages (from-to)384-388
Number of pages5
JournalClinical Endocrinology
Issue number3
StatePublished - Sep 1 2015

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


Dive into the research topics of 'Basal metabolic rate in women with PCOS compared to eumenorrheic controls'. Together they form a unique fingerprint.

Cite this