Keyphrases
Head-and-neck Cancer
100%
Head-and-neck Squamous Cell Carcinoma (HNSCC)
100%
Cell Survival
100%
Antitumor Efficacy
100%
Glutamine
100%
CPI-613
100%
Squamous Carcinoma Cells
71%
Glutaminase 1 (GLS1)
57%
Glutaminolysis
42%
CB-839
42%
Synergistic Therapy
28%
Metabolic Dependencies
28%
Cancer Cell Survival
14%
Dysregulated
14%
Immunohistochemistry
14%
Cancer Cells
14%
Metabolism
14%
In Cancer
14%
Short Hairpin RNA (shRNA)
14%
Enzyme Activity
14%
Glucose Uptake
14%
Western Blotting
14%
Cell Behavior
14%
Anticancer Activity
14%
Molecular Alterations
14%
Therapeutic Benefits
14%
Cell Surface Display
14%
Culture Dish
14%
Cell Viability
14%
Lentiviral
14%
Pyruvate Dehydrogenase
14%
Cell Culture
14%
Cell Apoptosis
14%
Glutathione Level
14%
Carcinoma Cell Lines
14%
Tumor-promoting
14%
Metabolic Changes
14%
Oxygen Consumption Rate
14%
Addiction
14%
Cancer Hallmarks
14%
Lactate Production
14%
Therapeutic Gain
14%
2D Culture
14%
Tricarboxylic Acid Cycle (TCA cycle)
14%
Lipoate
14%
3D Scaffold
14%
Cancer Targeting
14%
Cancer Metabolism
14%
α-ketoglutarate Dehydrogenase
14%
Metabolic Bypass
14%
Biochemistry, Genetics and Molecular Biology
Cell Survival
100%
Glutamine
100%
Glutaminase
100%
Glutaminolysis
75%
Cancer Cell
50%
Metabolic Pathway
50%
Anticancer
50%
Enzyme Activity
25%
Western Blot
25%
Cell Culture
25%
Animal Model
25%
Small Hairpin RNA
25%
Oxygen Consumption
25%
Pyruvate Dehydrogenase
25%
Citric Acid Cycle
25%
Glucose Transport
25%
Cell Viability
25%
Antineoplastic Activity
25%
Glutathione
25%
Oxidoreductase
25%
Dehydrogenase
25%